Research Keyword: host-microbe interactions

Strain-specific effects of Desulfovibrio on neurodegeneration and oxidative stress in a Caenorhabditis elegans PD model

This research shows that different strains of bacteria called Desulfovibrio have very different effects on brain health. When scientists exposed worms to six different strains, they found that environmental strains actually protected against Parkinson’s-like symptoms, while strains from human patients and animals caused more damage. The worms strongly preferred to eat the environmental strains, suggesting they could sense which bacteria were harmful. This highlights how the type of bacteria in our gut matters just as much as the total amount.

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The ATO gene family governs Candida albicans colonization in the dysbiotic gastrointestinal tract

This study shows that the fungus Candida albicans uses a family of protein transporters called ATO to absorb acetate, a fatty acid produced by gut bacteria. When mice were treated with antibiotics that killed their beneficial bacteria, C. albicans could colonize their guts better if it had working ATO transporters. The research reveals that fungi have evolved special systems to take advantage of nutrients left behind when the normal gut bacteria are disrupted, which helps explain why fungal infections are more common after antibiotic use.

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Human Gut Microbiome: A Connecting Organ Between Nutrition, Metabolism, and Health

Your gut bacteria function like an extra organ, helping digest food and producing important compounds that affect your whole body. The type of bacteria in your gut depends on diet, delivery method at birth, and antibiotics you’ve taken. Eating more fiber and taking certain probiotics can improve your bacterial balance and help prevent diseases like diabetes, obesity, and heart problems. This suggests that managing your gut microbiome through diet might be just as important as taking traditional medicines for staying healthy.

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Biofilms and Chronic Wounds: Pathogenesis and Treatment Options

Chronic wounds, such as diabetic foot ulcers and burn injuries, are often complicated by bacterial and fungal biofilms—protective communities of microorganisms that resist antibiotics and delay healing. This review summarizes how biofilms form, why they are difficult to treat with standard approaches, and discusses new therapeutic strategies. While debridement and antiseptics remain important, combining them with novel treatments like bacteriophages, enzyme therapies, and nanotechnology offers better chances for healing these stubborn wounds.

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Screening of yeasts in the oral microbiota of bats (Chiroptera) in Piauí, Brazil

Researchers collected oral samples from 47 bats in Brazil and found that over 40% carried yeast species, including some dangerous types like Candida albicans that cause infections in humans. The study identified that bats living near human settlements may serve as reservoirs for these disease-causing fungi, especially during rainy seasons when conditions favor yeast growth. This discovery highlights the importance of monitoring wildlife for infectious diseases to prevent them from spreading to humans.

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Phylogenetic and functional diversity among Drosophila-associated metagenome-assembled genomes

Researchers used advanced sequencing techniques to study the bacteria living in wild fruit flies collected from three continents. They discovered that these flies host diverse communities of bacteria that produce various compounds potentially beneficial to the fly, including antimicrobial molecules and metabolites that may help with nutrition and disease resistance. The study reveals that wild fly microbiomes are much more complex than previously understood from laboratory studies.

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