Research Keyword: histone modifications

Adaptive Changes and Genetic Mechanisms in Organisms Under Controlled Conditions: A Review

Organisms adapt to their environments through changes in their genes and how genes are expressed, processes that can happen over many generations even in laboratory settings. Scientists study these adaptations in fungi, insects, and plants grown under controlled conditions to understand how evolution works over shorter timeframes. The research shows that both genetic mutations and modifications to how genes work (without changing DNA itself) drive these adaptive changes. Understanding these mechanisms helps scientists improve crop productivity, develop disease resistance, and address environmental challenges like climate change.

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Transposons and accessory genes drive adaptation in a clonally evolving fungal pathogen

Researchers studied how a fungal plant pathogen called Fusarium oxysporum rapidly adapts to new environments by analyzing genetic changes during repeated passages through tomato plants and laboratory media. They discovered that jumping genes (transposons) were responsible for most mutations driving adaptation, and surprisingly found that genes located in specialized ‘accessory’ regions of the fungus’s genome controlled important functions like growth and virulence. This research reveals how fungal pathogens can evolve quickly to become better competitors or invaders.

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Comprehensive analysis of the mechanisms conferring resistance to phenamacril in the Fusarium species

Fusarium fungi cause serious diseases in crops like wheat, corn, and fruits, causing huge losses in agriculture worldwide. Phenamacril is a new antifungal drug designed specifically to fight these fungi by blocking a protein they need to grow. However, the fungi are developing resistance to this drug through genetic mutations and other biological mechanisms, making it less effective over time. Understanding how this resistance develops helps scientists develop better strategies to maintain the drug’s effectiveness and protect our food supply.

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