Heterocyclic compounds

Synthesis, Physicochemical Properties and Anti-Fungal Activities of New Meso-Arylporphyrins

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Researchers created three new porphyrin compounds that effectively kill fungal infections like Candida and athlete’s foot fungi. These compounds can also generate singlet oxygen when exposed to light, making them potentially useful for photodynamic therapy treatments. Testing showed they inhibited fungal growth at relatively low concentrations, suggesting they could become new antifungal medications.

Identification of two novel thiazolidin-2-imines as tyrosinase inhibitors: synthesis, crystal structure, molecular docking and DFT studies

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Scientists created two new chemical compounds that are much better at slowing down the enzyme tyrosinase, which is responsible for skin darkening and browning of foods. These compounds were tested both in the lab and using computer models, and they worked about 14 times better than kojic acid, a commonly used anti-darkening ingredient. The research suggests these new compounds could be useful in cosmetics, food preservation, and treating skin conditions like unwanted pigmentation.

Research Keyword: Heterocyclic compounds

Synthesis, Physicochemical Properties and Anti-Fungal Activities of New Meso-Arylporphyrins

Identification of two novel thiazolidin-2-imines as tyrosinase inhibitors: synthesis, crystal structure, molecular docking and DFT studies