heterocyclic chemistry

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

mycolabadmin

Scientists are searching for new treatments for COVID-19 by studying indole-containing compounds, which are found in many plants and can be made in laboratories. Some approved drugs with indole structures, like the antiviral drug Arbidol, have been repurposed to fight COVID-19. Researchers are also designing new indole compounds and using computer simulations to predict which ones might work best against the virus’s key proteins.

Design, synthesis, and antimicrobial evaluation of novel 1,2,4-triazole thioether derivatives with a 1,3,4-thiadiazole skeleton

mycolabadmin

Scientists created 17 new chemical compounds that can fight harmful fungi and bacteria that damage plants. One of these compounds, called 9d, proved to be even more effective than existing commercial pesticides at fighting plant diseases. Tests on kiwifruit showed that this new compound could protect and treat bacterial infections better than currently available treatments. These new compounds could help protect crops and reduce reliance on older pesticides.

Research Keyword: heterocyclic chemistry

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

Design, synthesis, and antimicrobial evaluation of novel 1,2,4-triazole thioether derivatives with a 1,3,4-thiadiazole skeleton