hepatoprotection – mycolab.ai

Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules

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Researchers developed a new health product combining three medicinal plants to protect the liver from injury. The mixture contains effective compounds that reduce liver inflammation, fight harmful oxidative stress, and protect liver cells from damage. Studies in rats showed the product improved liver function and reduced markers of liver damage, suggesting it could be useful for preventing and treating liver injuries caused by drugs, alcohol, or toxins.

Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts

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This study examined four types of edible mushrooms to see if they could protect against aging and fight harmful bacteria. Researchers gave mice an aging-inducing substance and then treated them with mushroom extracts. The mushrooms, particularly Lion’s Mane (Hericium erinaceus), helped prevent brain and liver damage, reduced inflammation, and showed antibacterial effects against multiple bacterial strains. These findings suggest mushrooms could be useful natural supplements to promote health and combat age-related decline.

Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities

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Mushrooms contain special compounds called polysaccharides that have powerful health benefits. Scientists have found these polysaccharides can help fight cancer, boost immunity, reduce inflammation, and manage diabetes. This review explains different ways to extract and purify these beneficial compounds from mushrooms and describes how they work in the body to provide these health benefits.

Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications

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Melanin from edible mushrooms like black wood ear and reishi offers a natural, sustainable alternative to synthetic melanins with impressive health benefits. These mushroom melanins demonstrate powerful antioxidant and antibacterial properties, protect against radiation damage, and can help maintain liver health. New extraction methods using special solvents are making it easier to obtain pure melanin from mushrooms efficiently, opening doors for its use in food, cosmetics, and medicines.

Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

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Scientists created tiny particles called zinc oxide nanoparticles using mushroom extract in an environmentally friendly way. These particles were tested and found to protect the liver from damage, kill harmful bacteria and fungi, and act as powerful antioxidants. This research suggests these mushroom-derived nanoparticles could become useful medicines for treating infections and cancer in the future.

Inonotus obliquus aqueous extract prevents histopathological alterations in liver induced by environmental toxicant Microcystin

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This research shows that Chaga mushroom extract can protect the liver from damage caused by microcystin, a toxic chemical produced by cyanobacteria in water. When mice were exposed to microcystin, their livers became damaged, but treating them with Chaga mushroom extract restored normal liver function and prevented cell death. The study suggests Chaga mushroom could be used as a natural supplement to prevent liver toxicity from environmental pollutants.

Evidence-Based Nutraceuticals Derived from Antrodia cinnamomea

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Antrodia cinnamomea, a mushroom from Taiwan traditionally used for health, contains many beneficial compounds that fight inflammation, tumors, and oxidative stress. Research shows it can help with cancer, liver disease, diabetes, and high blood pressure. The mushroom can be grown in laboratories and its active compounds extracted using various modern techniques, making it promising for health supplements and medicines.

The effect of chitosan supplementation on liver function, hepatic steatosis predictors, and metabolic indicators in adults with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled, clinical trial

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This study tested whether taking chitosan supplements (a type of dietary fiber) helps people with fatty liver disease. Over 8 weeks, participants taking chitosan along with a calorie-reduced diet lost more weight, reduced their waist size, and showed improvement in liver enzyme levels compared to those taking placebo. However, the supplement did not significantly improve cholesterol, blood sugar, or other metabolic markers at the dose tested.

Comparative Efficacy of Antrodia cinnamomea on Liver Function Biomarkers in Mice and Rats: A Network Meta-Analysis

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This study compared different extracts from a medicinal mushroom called Antrodia cinnamomea to see which ones work best for protecting liver health. Researchers analyzed data from multiple animal studies and found that extracts rich in compounds called triterpenoids were the most effective at improving liver function and reducing inflammation. The findings suggest that this mushroom could potentially become a natural treatment option for liver disease in the future.

Lipid Fraction from Agaricus brasiliensis as a Potential Therapeutic Agent for Lethal Sepsis in Mice

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Researchers tested a special extract from the Agaricus brasiliensis mushroom (rich in a compound called ergosterol) to treat severe sepsis, a life-threatening blood infection, in mice. When mice were given this mushroom extract alone, 67% survived, and when combined with antibiotics, 100% survived compared to none with saline alone. The extract reduced inflammation, protected the liver, fought bacteria, and reduced harmful free radicals in the body, suggesting it could be a valuable addition to antibiotic treatment for sepsis.

Research Keyword: hepatoprotection