Research Keyword: hematogenous dissemination

Disseminated sporotrichosis caused by Sporothrix brasiliensis with testicular involvement

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A 35-year-old homeless man with HIV developed a serious fungal infection caused by Sporothrix brasiliensis that spread throughout his body, including to his brain and testicles. A testicle lump was initially thought to be cancer and surgically removed, but it was actually a fungal infection. This is only the fifth case ever reported of this fungus infecting testicles. The patient was successfully treated with antifungal medications and remains healthy one year later.

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The impact of osteoarticular invasion by Coccidioides Sp disseminated infection

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A 48-year-old man from Mexico developed a serious fungal infection caused by Coccidioides, which spread from his lungs to his skin, bones, and joints, causing pain and swelling. Despite having a normally functioning immune system, he developed progressive disease that was initially misdiagnosed as rheumatoid arthritis. After switching to the antifungal medication fluconazole, his condition improved dramatically, with symptoms resolving within several months of treatment.

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Clinical Challenges and Predictive Risk Factors for Outcomes in COVID-19–Associated Mucormycosis

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During the COVID-19 pandemic, a dangerous fungal infection called mucormycosis has become a serious complication, especially for patients with uncontrolled diabetes or those taking certain medications. Researchers studied 180 patients with this condition and found that the infection can spread from the sinuses to the eyes and brain, leading to severe outcomes. The most important factors in surviving this infection are early detection, keeping blood sugar controlled, careful use of steroids, and aggressive treatment with antifungal medications and sometimes surgery.

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