Research Keyword: heart failure

Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes

Researchers tested whether magic mushrooms containing psilocybin could be safely used by people with heart failure, especially those dealing with depression. Using laboratory rat heart cells, they found that extracts from Psilocybe cubensis and Panaeolus cyanescens mushrooms actually protected heart cells from damage and reduced harmful inflammation. The mushroom extracts worked similarly to standard heart medications at the tested concentrations, suggesting they may be safe for use under controlled medical supervision.

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From Microbes to Myocardium: A Comprehensive Review of the Impact of the Gut-Brain Axis on Cardiovascular Disease

Your gut bacteria play a surprising role in heart health through a communication network called the gut-brain axis. When the balance of gut bacteria is disrupted (dysbiosis), it can lead to heart disease, high blood pressure, and clogged arteries. Beneficial bacteria produce helpful compounds like short-chain fatty acids that reduce inflammation and protect blood vessels, while harmful bacteria produce compounds that increase heart disease risk. Simple interventions like eating more fiber, taking probiotics, managing stress, and exercising can help maintain a healthy gut microbiome and improve heart health.

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