PRMT5 promotes cellulase production by regulating the expression of cellulase gene eg2 through histone methylation in Ganoderma lucidum
mycolabadmin
Scientists discovered that a protein called PRMT5 helps mushrooms (Ganoderma lucidum) produce more cellulase enzymes, which break down plant materials like corn straw and corn cobs. By controlling a specific gene called eg2 through a chemical modification on histone proteins, PRMT5 increases enzyme production. This discovery could help industries produce cellulase more efficiently and sustainably convert agricultural waste into useful sugars for biofuels and other products.