gut microbiota – Page 3

(Poly)phenol-gut microbiota interactions and their impact on human health

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Plant-based foods rich in polyphenols like berries, tea, and cocoa offer significant health benefits through interactions with gut bacteria. These bacteria break down polyphenols into active compounds that can help prevent heart disease, diabetes, and cancer. However, people respond differently to these foods based on their unique gut bacteria composition, suggesting the future of nutrition will be personalized based on individual microbial profiles.

Prebiotics and Probiotics Supplementation in Pigs as a Model for Human Gut Health and Disease

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Pigs are excellent models for studying human digestive health because their gut anatomy and function closely resemble humans. This review shows that prebiotics (special food compounds) and probiotics (beneficial bacteria) can improve gut health and strengthen the intestinal barrier in both healthy pigs and those with infections. These findings suggest that similar treatments might help prevent and treat digestive diseases in humans.

Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

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This study found that nettle polysaccharides, especially at lower doses, act as a natural supplement that boosts the body’s antioxidant defenses. The supplement works by promoting beneficial bacteria in the gut, which produce helpful metabolites that signal to the liver to enhance protective antioxidant enzymes. These findings suggest nettle polysaccharides could be a promising natural ingredient for health-conscious food products aimed at maintaining metabolic wellness.

Efficacy of prebiotic, probiotic and synbiotic administration in improving growth in children aged 0–59 months living in low- and middle-income countries: a systematic review and meta-analysis

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This comprehensive review examined whether giving children special dietary supplements containing beneficial bacteria and their food sources (prebiotics, probiotics, or synbiotics) helps them grow better in low-income countries. The analysis of eight studies found that these supplements may help children gain weight, especially those who are malnourished, though the evidence remains limited. More research is needed to fully understand whether these supplements are truly effective for promoting healthy growth in young children.

Regulatory effects of Lycium Barbarum polysaccharides on immune function and their application prospects

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Lycium barbarum, a plant used in traditional Chinese medicine for over 2000 years, contains special compounds called polysaccharides that boost the immune system. These compounds work by activating immune cells like macrophages and T cells, and can help fight infections and reduce inflammation. Research shows they may also help with conditions like arthritis, cancer, and gut health by acting as a natural prebiotic that promotes beneficial bacteria.

Interventions targeting the gut-liver axis: A potential treatment strategy for metabolic dysfunction-associated steatotic liver disease

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Your gut bacteria play a crucial role in liver health. When harmful bacteria build up in your gut, they can trigger liver inflammation and fat accumulation, leading to fatty liver disease. Researchers found that simple lifestyle changes like intermittent fasting, eating certain foods that feed good bacteria, and maintaining a healthy diet can restore healthy gut bacteria, strengthen your intestinal barrier, and reduce liver disease. This gut-focused approach could offer new ways to prevent and treat fatty liver disease beyond current treatments.

Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

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Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

Association of the use of nonfood prebiotics, probiotics, and synbiotics with total and cause-specific mortality: a prospective cohort study

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This study of over 53,000 American adults found that people taking nonfood supplements containing prebiotics, probiotics, or synbiotics had significantly lower risks of dying from any cause, heart disease, cancer, or other causes compared to those who didn’t take these supplements. The benefits were particularly strong in women and people without high blood pressure. These findings suggest that these supplement types may play an important role in preventing early death.

Gut Microbiome and Immune System Crosstalk in Chronic Inflammatory Diseases: A Narrative Review of Mechanisms and Therapeutic Opportunities

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Your gut contains trillions of bacteria that play a crucial role in keeping your immune system balanced. When this bacterial community becomes imbalanced (dysbiosis), it can lead to chronic inflammatory diseases like arthritis, inflammatory bowel disease, psoriasis, and lupus. Recent research shows that restoring a healthy gut microbiota through diet, probiotics, prebiotics, or fecal transplants may help treat these conditions by reducing inflammation and strengthening the gut barrier.

Winning the battle of intestinal peace with Bacillus—a multifaceted approach to animal health, immunity, and future applications in monogastric livestock production

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This review examines how Bacillus bacteria, when added to animal feed, can improve the health and growth of chickens and pigs. These bacteria work by producing beneficial compounds that strengthen the gut, improve digestion, reduce harmful bacteria, and boost the immune system. Bacillus probiotics offer a natural alternative to antibiotics, helping reduce antibiotic resistance while keeping animals healthier and more productive.

Research Keyword: gut microbiota