gut microbiota modulation

The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

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Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

Impact of a Limosilactobacillus fermentum, Quercetin, and Resveratrol Nutraceutical on Fecal Microbiota Composition and Metabolic Activity in Healthy and Hypertensive Subjects

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Researchers tested a dietary supplement containing beneficial bacteria and plant compounds on human gut microbiota samples. The supplement successfully modified the composition and activity of gut bacteria in both healthy and high blood pressure patients. The supplement increased production of beneficial acids and modified which bacteria were present in the fermentation samples. These findings suggest this type of supplement could potentially help manage high blood pressure by improving gut health.

Dietary melanoidins as emerging functional components: interactions with gut microbiota and implications for nutritional modulation of intestinal health

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Melanoidins are natural brown compounds formed when foods are cooked or fermented, found in items like roasted coffee, bread, and soy sauce. When eaten, these compounds pass through the stomach and small intestine unchanged, then are broken down by beneficial bacteria in the colon. This breakdown produces helpful substances that support gut health, reduce inflammation, and may help prevent digestive diseases like irritable bowel syndrome and inflammatory bowel disease.

The Role of Nutraceuticals and Probiotics in Addition to Lifestyle Intervention in the Management of Childhood Obesity—Part 1: Metabolic Changes

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This review examines how natural compounds and beneficial bacteria can help obese children improve their metabolic health when combined with diet and exercise changes. Key findings show that supplements like white mulberry leaf extract and special fiber products can help reduce weight, improve blood sugar control, and lower cholesterol. The evidence suggests these natural interventions are promising but need more large-scale studies in children to confirm their effectiveness and optimal dosing.

Potential Roles of Exogenous Proteases and Lipases as Prebiotics

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This review explores how digestive enzymes like proteases and lipases work similarly to prebiotics—foods that feed beneficial bacteria in your gut. When animals consumed supplements of these enzymes, their gut bacteria became healthier, producing more beneficial compounds and showing improved intestinal health. These findings suggest that fermented foods and raw foods containing natural digestive enzymes, as well as enzyme supplements, may help promote a healthy gut microbiome.

Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

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This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

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This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

Anti-Hyperlipidemic and Anti-Atherogenic Effect of Citrus Peel Pectin Against Cholesterol and Cholic Acid Induced Hyperlipidemia in Sprague Dawley Rats

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Researchers tested whether pectin extracted from citrus peels could help treat high cholesterol and fat levels in the blood using rats. When rats were given different amounts of citrus peel pectin mixed into their food, their cholesterol and triglyceride levels decreased significantly while their good cholesterol (HDL) increased. The treatment also protected their heart, liver, and kidney tissues from damage. This suggests citrus peel pectin, usually thrown away by juice companies, could become a useful and natural remedy for managing high cholesterol.

Research Keyword: gut microbiota modulation