Research Keyword: glyoxylate cycle

Is metabolic generalism the Breakfast of Champions for pathogenic Candida species?

This review examines how different Candida species, including the common cause of yeast infections (C. albicans) and the more dangerous bloodstream pathogen (C. glabrata), survive in the human body. While most pathogenic Candida species are metabolic generalists that can eat many different nutrients, the review shows that C. glabrata is a specialist that has found alternative strategies to thrive. Understanding these metabolic strategies is important for developing better treatments and fighting antifungal resistance.

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Unveiling molecular mechanisms of strobilurin resistance in the cacao pathogen Moniliophthora perniciosa

This research reveals how a fungus that causes disease in cacao plants survives treatment with strobilurin fungicides, which are commonly used in agriculture. Scientists discovered that the fungus adapts by reorganizing its metabolism to compensate for the drug’s effects, activating detoxification systems, and in some cases, developing genetic mutations that enhance resistance. Understanding these survival mechanisms could help develop better strategies to control this economically important crop disease.

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