Research Keyword: glycoside hydrolase

Exo- and Endo-1,5-α-L-Arabinanases and Prebiotic Arabino-Oligosaccharides Production

This review explores arabino-oligosaccharides (AOS), special sugar compounds that act as prebiotics to feed beneficial gut bacteria. Scientists use enzymes called arabinanases to produce these AOS from plant material, particularly from arabinan found in sugar beets. Different types of these enzymes create different AOS products with varying health benefits, making them promising ingredients for functional foods and supplements that support digestive health.

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Functional Approaches to Discover New Compounds via Enzymatic Modification: Predicted Data Mining Approach and Biotransformation-Guided Purification

Scientists are developing faster ways to discover new medicines from plants using two innovative methods. The first approach uses computer programs to predict which plant compounds can be chemically modified by enzymes to create new medicines with better properties. The second approach combines enzyme chemistry with traditional purification to directly isolate these modified compounds from plant extracts. These methods have successfully created new compounds with improved effectiveness against diseases like diabetes and cancer, often with much better solubility for medical use.

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Haplotype-resolved genomes of Phlebopus portentosus reveal nuclear differentiation, TE-mediated variation, and saprotrophic potential

Scientists sequenced the complete genomes of two compatible strains of the king bolete mushroom (Phlebopus portentosus), an important edible and medicinal species. The study found that mobile DNA elements called transposons play a major role in creating genetic differences between the two fungal nuclei and in generating the diversity of compounds that give mushrooms their health benefits. The research shows this mushroom can both partner with trees and break down organic material on its own, making it uniquely adaptable.

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