Research Keyword: genomic sequencing

The complete mitochondrial genome of medicinally important wood-decaying fungus Tyromyces fissilis within the family Incrustoporiaceae, Polyporales

mycolabadmin

Scientists have sequenced the complete genetic blueprint of a wood-rotting mushroom called Tyromyces fissilis for the first time. This fungus is medicinally important and has the ability to break down wood and produce therapeutic compounds. By analyzing its mitochondrial genome and comparing it with related fungi, researchers found that it is most closely related to another fungus called Phlebia radiata and belongs to a previously understudied fungal family. This genetic information will help scientists better understand how these fungi are related and may lead to new medical applications.

Read More »

Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast

mycolabadmin

Scientists successfully engineered baker’s yeast to produce ganoderic acids, potent anti-cancer compounds from medicinal mushrooms, at much higher levels than found in farmed mushrooms. By identifying key enzymes responsible for converting simpler compounds into active ganoderic acids, researchers created yeast strains that produce these valuable compounds 100-10,000 times more efficiently than traditional mushroom farming. This breakthrough could make these expensive medicinal compounds more accessible and affordable for medical research and potential drug development.

Read More »

Complete mitochondrial genome of the fungal pathogen Fusarium oxysporum f. sp. palmarum responsible for fusarium wilt of palms

mycolabadmin

Scientists sequenced the complete genetic material found in the mitochondria of a fungus called Fusarium oxysporum that causes a disease in palm trees. This fungus, which was collected from a sick Mexican fan palm in Florida, destroys palm fronds and can kill the tree. By mapping out this genetic information, researchers now have a better tool to quickly identify and track this harmful pathogen, which will help protect ornamental palm trees.

Read More »

A high-quality genome assembly of Lactarius hatsudake strain JH5

mycolabadmin

Scientists have completed a detailed genetic blueprint of the red milk mushroom (Lactarius hatsudake), an edible and medicinal fungus that grows in pine forests. This mushroom is nutritious and has been shown to help with diabetes, boost immunity, and fight harmful bacteria. The new genetic map is much more complete and detailed than previous versions, which will help farmers grow these valuable mushrooms more reliably and sustainably, and could lead to developing better varieties.

Read More »

Infection caused by a cryptic fungal species, Blastomyces gilchristii, in a tiger

mycolabadmin

A tiger at a veterinary hospital developed a serious fungal infection that affected its brain and lungs. Using advanced DNA sequencing technology, researchers identified the infection was caused by a previously unrecognized fungal species called Blastomyces gilchristii. This discovery was important because it showed that this dangerous fungus exists in areas where scientists previously thought it wasn’t found, and it highlights the importance of using modern genetic testing to identify unusual infections.

Read More »

Simultaneous Detection of Four Madurella Species Using Loop-Mediated Isothermal Amplification (LAMP) for Eumycetoma Diagnosis

mycolabadmin

Scientists developed a simple new test to identify four types of fungi that cause a serious tropical disease called eumycetoma. Unlike previous tests that required expensive equipment and multiple reactions, this new test works in one tube using simple heating instead of complex thermal cycling. The test can detect the fungi in about 45 minutes and works reliably in remote areas with limited resources.

Read More »
Scroll to Top