Research Keyword: genomic characterization

Draft genome sequences of five endophytic fungi isolated from Lactuca serriola, a wild relative of cultivated lettuce

Researchers sequenced the genomes of five fungal species found living inside wild lettuce plants collected in Arizona. These endophytic fungi can potentially improve the growth and disease resistance of cultivated lettuce. The study identified genetic clusters that produce compounds similar to known natural products, which could affect how these fungi interact with plants. This genomic information provides a foundation for future research into using these beneficial fungi as natural inoculants for improving lettuce crops.

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Brown locusts, Locustana pardalina, host fluconazole-resistant Candidozyma (Candida) auris, closely related to Clade III clinical strains

Scientists found that brown locusts in South Africa carry a dangerous yeast called Candida auris that is resistant to the antifungal drug fluconazole. This yeast is similar to strains that infect hospital patients and is highly adaptable, surviving extreme temperatures and salt levels found in locust guts. This discovery suggests that insects like locusts could play a role in spreading this emerging fungal pathogen in nature, which has important implications for understanding how dangerous microbes spread between animals and humans.

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Genomic characterization and fermentation study of the endophyte Stemphylium sp. (Aa22), a producer of bioactive alkyl-resorcinols

Scientists sequenced the complete genome of a fungus called Stemphylium sp. (strain Aa22) that lives inside wormwood plants without harming them. This fungus produces natural compounds called alkyl-resorcinols that can repel aphids and kill plant-damaging nematodes, making them potentially useful as organic pesticides. The researchers found the genetic instructions for making these compounds and determined that growing the fungus in liquid culture produces more of the useful compounds than growing it on rice, offering a promising path toward developing these natural biopesticides on a larger scale.

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Brown locusts, Locustana pardalina, host fluconazole-resistant Candidozyma (Candida) auris, closely related to Clade III clinical strains

Researchers discovered that brown locusts in South Africa can carry a dangerous drug-resistant fungus called Candida auris in their digestive systems. This fungus, which causes serious infections in hospitals and is resistant to the antifungal drug fluconazole, may use locusts as a way to spread to humans or other environments. The study suggests that insects could play an important role in how dangerous fungi emerge and spread globally, particularly in warm climates where locusts thrive.

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