Research Keyword: genome assembly

The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

Scientists have sequenced the complete genome of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research reveals the mushroom’s genetic blueprint, including genes responsible for producing beneficial compounds and adapting to rocky mountain environments. This foundational work aims to enable sustainable cultivation of this rare fungus and development of new medicinal treatments, addressing current conservation threats from over-harvesting.

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Comparative genome analysis of patulin-producing Penicillium paneum OM1 isolated from pears

This research examined the genetic makeup of a mold called Penicillium paneum that contaminates pears and apples by producing a toxic substance called patulin. Scientists sequenced the entire genome and identified all the genes responsible for patulin production. They found that this mold has 33 different gene clusters for producing various toxic compounds, with the patulin-producing genes being highly similar to those in other related molds. This genetic knowledge could help develop better strategies to prevent patulin contamination in fruit crops.

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The mitochondrial genome of a wild edible mushroom, Russula rosea

Scientists sequenced the complete genetic instructions contained in the energy centers (mitochondria) of Russula rosea, a wild edible mushroom known for its antioxidant and anti-tumor properties. The mushroom’s mitochondrial genome contains 57 genes and is about 54,177 DNA base pairs long. By comparing this genetic information with other fungi, researchers found that Russula rosea is closely related to another mushroom species called Russula lepida. This discovery helps scientists better understand how edible mushrooms are related to each other evolutionarily.

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Haplotype-Phased Chromosome-Level Genome Assembly of Floccularia luteovirens Provides Insights into Its Taxonomy, Adaptive Evolution, and Biosynthetic Potential

Scientists have created the most detailed genetic map of the yellow mushroom (Floccularia luteovirens), a highly valued medicinal and edible fungus from the Tibetan Plateau. Using advanced sequencing technology, they mapped its 13 chromosomes and identified 15 pathways that the mushroom uses to make potentially useful healing compounds. The research also solved a long-standing mystery about the mushroom’s family tree, proving it is not actually related to Armillaria mushrooms as previously thought. This genetic blueprint opens new possibilities for developing medicines from this special fungus.

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Saprotrophic Arachnopeziza Species as New Resources to Study the Obligate Biotrophic Lifestyle of Powdery Mildew Fungi

Scientists have created a new way to study powdery mildew fungus, which causes widespread plant disease but cannot normally be studied in the laboratory. They identified a related fungus species (Arachnopeziza) that can grow in culture and can be genetically modified. By sequencing the DNA of these two Arachnopeziza species and developing methods to alter their genes, researchers have created a practical tool to understand how powdery mildew becomes dependent on its plant host, potentially leading to better disease control strategies.

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Draft genome sequences for four isolates of the hemp (Cannabis sativa) fungal pathogen Neofusicoccum parvum

Scientists sequenced the complete genomes of four samples of a fungal disease that infects hemp plants. This fungus, called Neofusicoccum parvum, causes dying branches and damage to hemp crops. By mapping out the genetic code of these fungal samples, researchers now have important tools to better understand how this pathogen works and potentially develop strategies to protect hemp plants.

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Comparison and Analysis of the Genomes of Three Strains of Botrytis cinerea Isolated from Pomegranate

Researchers compared three strains of gray mold fungus (Botrytis cinerea) that infect pomegranate fruits from different regions in Mexico. Using DNA sequencing and laboratory tests, they found that the MIC strain from Hidalgo was more aggressive at infecting fruit and breaking down plant tissues than the other two strains from the State of Mexico. These differences appear related to each strain’s genetic makeup and where they originated, which could help farmers develop better strategies to prevent gray mold disease on pomegranates.

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Whole-genome sequencing of global forest pathogen Diplodia sapinea causing pine shoot blight

This study presents a detailed genetic map of Diplodia sapinea, a fungus that causes serious disease in pine trees worldwide. Researchers sequenced the complete genome of a strain from China and compared it with related fungi to better understand how the pathogen causes disease. The high-quality genetic information provides important tools for scientists to develop better ways to prevent and control pine shoot blight, protecting valuable forests and timber resources.

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Draft genome sequence of Leptobacillium coffeanum (Cordycipitaceae, Hypocreales), a freshwater fungus isolated from Bohol, Philippines

Scientists in the Philippines have sequenced the complete genetic code of a freshwater fungus called Leptobacillium coffeanum, which was found in forest streams in Bohol. This fungus belongs to a family of fungi that can help control pests and produce useful compounds for agriculture and medicine. The complete genetic information is now available to researchers worldwide for studying how this fungus works and finding new ways to use it for practical applications.

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