Research Keyword: genetic variation

Natural expression variation for the Arabidopsis MED20a mediator complex subunit influences quantitative resistance to Sclerotinia sclerotiorum

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Scientists studied how different varieties of a common plant (Arabidopsis) naturally resist a destructive fungal disease caused by Sclerotinia sclerotiorum. By examining genetic differences among plant varieties and testing a fungus from different sources, they found that a gene called MED20a plays an important role in disease resistance. Plants with specific genetic variations in the MED20a gene’s control region were more resistant to infection.

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Genetic variation among progeny shapes symbiosis in a basidiomycete with poplar

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This research examines how different genetic variations within a single fungal species affect its ability to form beneficial partnerships with poplar tree roots. Scientists studied 40 genetically distinct fungal strains derived from the same parent and found that they varied greatly in their success at colonizing tree roots, ranging from complete failure to excellent colonization. By analyzing the genes and gene expression of these strains, the team identified specific genetic regions that influence symbiosis formation and discovered that genetic diversity within this fungal species plays an important role in how effectively forest ecosystems function.

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Genetic and Genomic Analysis Identifies bcltf1 as the Transcription Factor Coding Gene Mutated in Field Isolate Bc116, Deficient in Light Responses, Differentiation and Pathogenicity in Botrytis cinerea

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Scientists identified the genetic mutation responsible for unusual traits in a fungal strain (Bc116) that causes grape disease. The mutation in the bcltf1 gene prevents the fungus from infecting plants when exposed to light, while making it produce excessive spores and form smaller seed structures. By restoring the normal gene in laboratory experiments, researchers confirmed that this single gene controls multiple important fungal behaviors related to light sensing and disease-causing ability.

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Gut fungi are associated with human genetic variation and disease risk

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Researchers discovered for the first time how human genes influence the fungi living in our gut and how this connection affects heart disease risk. They found that a yeast called Kazachstania is regulated by a gene called CDH13, and people with certain genetic variants have less of this beneficial yeast and higher risk of heart disease. This groundbreaking study shows that our genetics don’t just affect bacteria in our gut—they also shape our fungal community, which has real implications for heart health.

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