Research Keyword: gene targeting

Functional analysis of enhancer elements regulating the expression of the Drosophila homeodomain transcription factor DRx by gene targeting

Scientists studied how a specific gene called DRx is controlled during fruit fly brain development. They identified the DNA regions called enhancers that turn on this gene at different times and in different parts of the developing brain. By removing these enhancers one at a time, they showed which brain structures depend on each enhancer, revealing that DRx plays important roles in multiple aspects of brain formation.

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