Research Keyword: gene knockout

A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua

Cordyceps chanhua is a medicinal fungus used in traditional Chinese medicine that produces a compound called beauvericin, which has health benefits but can be toxic in high amounts. Researchers discovered a gene called CcT1 that controls how much beauvericin the fungus makes. By removing this gene, they could reduce beauvericin production by 64%, making the fungus safer to use as medicine while maintaining other beneficial properties.

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