Research Keyword: gene expression

In vitro and in vivo inhibitory effects and transcriptional reactions of graphene oxide on Verticillium dahliae

Graphene oxide, a nanomaterial derived from graphene, effectively inhibits the growth of Verticillium dahliae, a fungus that causes devastating wilt disease in cotton and many other plants. The study shows that graphene oxide damages the fungal cell membrane and disrupts key metabolic processes, preventing the fungus from growing and infecting plants. When applied to cotton plants, graphene oxide treatment significantly reduced wilt disease symptoms, suggesting it could be a promising alternative to chemical fungicides for controlling this important agricultural disease.

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Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

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Citric acid impairs type B trichothecene biosynthesis of Fusarium graminearum but enhances its growth and pigment biosynthesis: transcriptomic and proteomic analyses

Citric acid, a compound found in plant roots, has an interesting dual effect on a dangerous fungus called Fusarium graminearum that destroys grain crops worldwide. While citric acid helps the fungus grow better, it actually prevents the fungus from producing dangerous toxins called trichothecenes. This finding suggests that citric acid could potentially be used in farming to reduce the harmful toxins that contaminate wheat and corn while maintaining reasonable fungal control.

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Integration of Metabolomes and Transcriptomes Provides Insights into Morphogenesis and Maturation in Morchella sextelata

Researchers studied how morel mushrooms develop from mycelium through fruiting body maturation by analyzing changes in their metabolites and genes across four growth stages. They found that the transition from vegetative growth to reproductive growth involves dramatic changes in carbohydrate, amino acid, and lipid metabolism, regulated by specific transcription factors. This understanding could help improve the cultivation of morels, which currently struggles with low fruiting rates despite their high value as food and medicine.

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Transcriptome and metabolome profiling reveal the inhibitory effects of food preservatives on pathogenic fungi

This research tested three common food preservatives to see how well they stop harmful molds from growing on fruits and vegetables. Scientists found that all three preservatives worked well at different concentrations, with sec-butylamine being particularly effective. By studying the genes and chemical changes in treated fungal cells, they discovered that these preservatives work by damaging the mold’s cell walls and disrupting how it processes sugars, essentially starving and weakening the fungal cells.

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Influences of substrate and tissue type on erinacine production and biosynthetic gene expression in Hericium erinaceus

This study examined how different growing conditions and tissue types affect erinacine production in lion’s mane mushrooms. Researchers found that mycelium (the fungal threads) produced far more erinacines than fruit bodies, and that the type of growth medium significantly influenced which erinacines were produced. Interestingly, changes in erinacine production weren’t always reflected in gene activity levels, suggesting other cellular mechanisms control these beneficial compounds.

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Transcriptome Reveals the Key Genes Related to the Metabolism of Volatile Sulfur-Containing Compounds in Lentinula edodes Mycelium

Researchers studied how shiitake mushroom mycelium develops its characteristic sulfur-containing flavor during early growth stages. They found that the first 15 days of mycelial growth produce the most volatile flavor compounds, similar to those found in mature mushrooms. Using advanced genetic analysis and computer modeling, they identified two key genes (Leggt3 and Lecsl3) responsible for producing these flavor compounds. This research suggests that mushroom mycelium could be cultivated as an efficient source for producing shiitake flavor compounds for use in food additives and flavorings.

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Transcriptomic and metabolic profiling reveals adaptive mechanisms of Auricularia heimuer to temperature stress

Researchers studied how a popular edible mushroom called black wood ear (Auricularia heimuer) adapts to different temperatures. They found that the mushroom grows best at 35°C but struggles at very cold (15°C) or extremely hot (45°C) temperatures. By analyzing the genes and chemicals produced by the mushroom at different temperatures, scientists discovered that the mushroom uses different survival strategies depending on how hot or cold it is, which could help farmers grow better mushrooms.

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Interference with sexual mating of Sporisorium scitamineum by verrucarin A isolated from Paramyrothecium sp

Scientists discovered a fungus from moss that produces a natural compound called verrucarin A, which stops sugarcane smut disease by preventing the sexual mating of its fungal spores. This prevents the disease from developing without harming the sugarcane plants. In greenhouse tests, this natural biocontrol agent reduced disease occurrence by nearly half compared to untreated plants, offering a safe alternative to chemical pesticides for protecting sugarcane crops.

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Genetic regulation of l-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis

Researchers studied how magic mushrooms (Psilocybe mexicana) control their chemical processes to make psilocybin. They found that when mushrooms start producing psilocybin, they turn on genes that make more of an amino acid called tryptophan, while turning off genes that would break it down. They also discovered and studied an enzyme that helps control tryptophan use. This understanding could help grow these mushrooms with more consistent psilocybin levels for legitimate medical research into treating depression.

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