gene expression analysis

Function of Transcription Factors PoMYB12, PoMYB15, and PoMYB20 in Heat Stress and Growth of Pleurotus ostreatus

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This research explores how specific genes in oyster mushrooms help them survive and grow better when exposed to heat stress. Scientists created mutant mushroom strains by either increasing or decreasing expression of three genes called PoMYB12, PoMYB15, and PoMYB20. They found that boosting PoMYB12 and PoMYB20 made mushrooms more heat-resistant and grow faster, while reducing PoMYB15 had similar beneficial effects. These discoveries could help farmers grow better oyster mushrooms during hot summer months when heat damage is a major problem.

Antimicrobial and prebiotic properties of Weissella confusa B4-2 exopolysaccharide and its effects on matrix metalloproteinase genes expression

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Researchers discovered that a bacterium called Weissella confusa produces a sticky substance (exopolysaccharide) that has multiple health benefits. This substance fights harmful bacteria, acts as an antioxidant, helps heal wounds, and may slow down skin aging by reducing proteins that break down collagen. Because this bacterium produces much more of this substance than other commonly studied bacteria, it could be used in food preservation, health supplements, and anti-aging skincare products.

Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

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A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

Efficacy of Trichoderma longibrachiatum SC5 Fermentation Filtrate in Inhibiting the Sclerotinia sclerotiorum Growth and Development in Sunflower

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Scientists studied a beneficial fungus called Trichoderma longibrachiatum that can fight a harmful mold (Sclerotinia sclerotiorum) which damages sunflower crops. They discovered that liquid containing products from this beneficial fungus can significantly stop the harmful mold from growing, prevent it from forming protective survival structures called sclerotia, and reduce its ability to infect plants. When tested on sunflower leaves, this fungal liquid was highly effective at both preventing disease before infection and stopping disease after infection had started.

Bioremediation potential of low-brominated polybrominated diphenyl by the phyllospheric Wickerhamomyces anomalus

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Researchers discovered that a common yeast living on tree leaves can help remove harmful brominated chemicals (PBDEs) from the environment. By studying the genes this yeast uses to survive these toxic chemicals, scientists identified a key transport protein that could help plants better tolerate and accumulate these pollutants. This finding suggests that this yeast could be used as a biological tool to clean up areas contaminated with these persistent toxic chemicals.

The Potential of Transgenic Hybrid Aspen Plants with a Recombinant Lac Gene from the Fungus Trametes hirsuta to Degrade Trichlorophenol

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Scientists created genetically modified aspen trees that contain an enzyme from a fungus which breaks down toxic chlorophenol chemicals in soil. These transgenic trees were much more effective at removing these harmful pollutants than regular trees. Three of the modified tree lines worked well without causing problems for the plants themselves, suggesting they could be used to clean up contaminated soil in polluted areas.

Potential of Wormwood and Oak Bark-Based Supplement in Health Improvement of Nosema ceranae-Infected Honey Bees

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This study tested a natural dietary supplement made from wormwood and oak bark on honey bees infected with Nosema ceranae, a parasite that weakens bee colonies. The supplement significantly improved bee survival and reduced parasite levels, regardless of when it was given. It also reduced harmful oxidative stress caused by the infection. While it didn’t boost immune genes as strongly as some other treatments, its plant-based nature and consistent effectiveness make it a promising tool for beekeepers.

Overexpression of efflux pump and biofilm associated genes in itraconazole resistant Candida albicans isolates causing onychomycosis

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Nail fungal infections caused by Candida albicans can be difficult to treat when the fungus becomes resistant to common antifungal medications like itraconazole. Researchers found that resistant strains have overactive genes that pump the drug out of fungal cells and genes that help the fungus form protective biofilm structures. Understanding these resistance mechanisms could lead to better combination treatments that block these protective strategies.

Molecular characterization of gliotoxin synthesis in a biofilm model of Aspergillus fumigatus

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Researchers studied how a dangerous fungus called Aspergillus fumigatus produces a toxin called gliotoxin when it forms biofilms, which are organized communities of fungal cells found in human infections. They compared two clinical strains from infected patients and found they produced gliotoxin at different times and in different amounts, despite forming similar biofilm structures. By analyzing which genes were turned on and off, they discovered that one strain rapidly produced toxin early while the other strain produced it more slowly, suggesting different strategies for survival. Understanding these differences could help develop better treatments for serious lung infections caused by this fungus.

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

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Scientists tested a plant-based extract from Cinchona bark as a natural fungicide against a serious fungus that damages rice crops. The active ingredient, quinine, works by two methods: it blocks the fungus from getting the amino acid tryptophan it needs to survive, and it damages the fungus’s energy-producing structures. When researchers added tryptophan back to the treated fungus, it recovered, confirming this is how the treatment works. This natural fungicide could offer farmers an eco-friendly alternative to chemical pesticides.

Research Keyword: gene expression analysis