gene expression – mycolab.ai

Upregulation of ACC deaminase gene in Bacillus velezensis UTB96 improved yield and shelf Life of Agaricus bisporus

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Researchers developed a way to improve button mushroom production using a beneficial bacterium treated with calcium chloride. This treatment boosts the bacteria’s ability to reduce ethylene, a natural plant hormone that causes mushrooms to age quickly. The treated mushrooms showed 23% higher yields and stayed fresh for at least three weeks in storage without browning, making them more appealing to consumers.

In-ovo injection of Bacillus subtilis, raffinose, and their combinations enhances hatchability, gut health, nutrient transport- and intestinal function-related genes, and early development of broiler chicks

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Researchers injected newly developing chicken eggs with beneficial bacteria (Bacillus subtilis) and a prebiotic substance (raffinose) to improve chick health. The treatment enhanced egg hatchability, improved chick weight, reduced harmful bacteria in the gut, and strengthened intestinal function. This approach shows promise as a natural alternative to antibiotics in poultry farming.

The Transformation and Protein Expression of the Edible Mushroom Stropharia rugosoannulata Protoplasts by Agrobacterium-tumefaciens-Mediated Transformation

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Scientists developed a genetic engineering technique to modify king stropharia (a cultivated edible mushroom) by inserting foreign genes into its cells. This breakthrough allows researchers to study how the mushroom grows and produces beneficial compounds. The technique uses a bacterium called Agrobacterium tumefaciens to naturally deliver genes into mushroom cells, similar to how it infects plants. This advancement could lead to improved cultivation practices and enhanced nutritional or medicinal properties.

Investigation of Efficient Pullulan Synthesis Utilizing Huangjiu Lees as a Substrate

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Scientists have discovered a way to use Huangjiu lees, the waste material left over from making Chinese rice wine, to produce pullulan, a valuable biopolymer used in food and medicine. By evolving a special fungal strain through repeated exposure to these lees, they created a strain that produces pullulan much more efficiently. Using optimized fermentation conditions and a two-stage process with different microorganisms, they achieved significantly higher pullulan yields, making this previously discarded byproduct into a valuable resource.

Genome-wide identification of PSKR genes in wheat and differential expression under abiotic stress conditions

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Scientists identified 149 genes related to phytosulfokine receptors (PSKR) in wheat that help plants respond to environmental stresses like drought, salt, cold, and heat. These genes are spread across wheat’s chromosomes and contain regulatory elements that control their expression in response to various stresses and plant hormones. The study provides important genetic resources for developing wheat varieties that are more resistant to environmental stress, which is crucial for maintaining crop productivity in changing climate conditions.

Exploring the Mechanisms of Amino Acid and Bioactive Constituent Formation During Fruiting Body Development in Lyophyllum decastes by Metabolomic and Transcriptomic Analyses

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This research study examined how Lyophyllum decastes mushrooms develop and accumulate their valuable nutrients and flavor compounds. Scientists found that amino acids and polysaccharides reach their highest levels when the mushroom is mature, ready for harvesting. By analyzing the genes and chemical changes during mushroom growth, researchers identified the specific pathways responsible for producing these beneficial compounds. This knowledge helps improve mushroom cultivation and confirms its value as a healthy functional food.

Prognostic model for gastric cancer patients with COVID-19 and network pharmacology study on treatment by lentinan

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This study investigated how lentinan, a compound from shiitake mushrooms, might help treat patients who have both gastric cancer and COVID-19. Researchers identified five genes that predict patient outcomes and found that lentinan may work by controlling immune cell activity and reducing inflammation. The study suggests lentinan could be a useful additional treatment for this challenging combination of diseases, though more research is needed.

Fatty acid synthesis: A critical factor determining mycelial growth rate in Pleurotus tuoliensis

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Researchers studied why Pleurotus tuoliensis mushrooms grow slowly compared to other oyster mushroom species. They found that a key enzyme called acetyl-CoA carboxylase, which controls fat production in the mushroom cells, directly affects how fast the mycelium grows. By increasing this enzyme’s activity and providing nutrients that help fat-making, scientists were able to boost mycelial growth rates significantly, offering new strategies to improve commercial cultivation of these delicious mushrooms.

Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects

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This study examined whether taking the antidepressant escitalopram before using psilocybin affects the drug’s effects. Twenty-three healthy participants took either escitalopram or placebo for two weeks, then received a dose of psilocybin. Surprisingly, escitalopram did not reduce the positive mood effects of psilocybin and actually reduced some negative side effects like anxiety and bad feelings. The combination appeared safe with no increased cardiovascular risks.

Long-COVID symptoms improved after MDMA and psilocybin therapy: A case report

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A 41-year-old woman with Long-COVID experienced severe symptoms including fatigue, depression, anxiety, headaches, and brain fog that didn’t improve with traditional treatments. She decided to try psilocybin mushrooms and MDMA with guidance from a therapist. After multiple dosing sessions over several months, she reported roughly 80-90% improvement in her symptoms and was able to return to work and resume her studies. While this single case is promising, more research is needed to determine whether these psychedelics are truly safe and effective for Long-COVID.

Research Keyword: gene expression