Ganoderma lucidum – mycolab.ai

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

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Ganoderma lucidum, a mushroom used in traditional medicine for thousands of years, shows promise in fighting certain blood cancers like leukemia and lymphoma. The mushroom contains special compounds that can kill cancer cells in multiple ways—by triggering cancer cell death, boosting the immune system, and preventing cancer cell growth. While laboratory studies are very encouraging, more testing in humans is needed before it can be used as a standard cancer treatment.

Characterisation and Hypolipidaemic Effects of Tlayudas, Widely Consumed Tortillas, Containing Ganoderma lucidum Extracts on an In Vivo Model of Hypercholesterolaemia

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Researchers created an improved version of tlayudas, a traditional Mexican tortilla, by adding extracts from the medicinal mushroom Ganoderma lucidum. When mice were fed a high-cholesterol diet with these enhanced tlayudas, they experienced significant reductions in cholesterol and triglycerides comparable to or better than pharmaceutical treatments. These functional foods could help Mexican communities reduce their risk of heart disease and other health problems related to diet.

Benzothiazole—An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides

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Scientists discovered that a chemical called benzothiazole found in the medicinal mushroom Ganoderma lucidum can effectively kill the fungus that causes mango anthracnose, a major disease affecting mango crops. The research showed that this natural compound completely stops fungal growth at very low concentrations (50 ppm) and prevents spore germination. This discovery offers a promising eco-friendly alternative to synthetic fungicides that can cause environmental pollution and drug resistance.

Ultrasound-assisted extraction of neuroprotective antioxidants from Ganoderma lucidum

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This research studied how to best extract healing compounds from the reishi mushroom (Ganoderma lucidum), an important traditional Chinese medicine. Using advanced extraction techniques and computer modeling, scientists identified optimal conditions that doubled the amount of beneficial antioxidants obtained compared to conventional methods. They then tested these extracts on nerve cells in the laboratory, demonstrating that the extracts effectively protected cells from oxidative damage and injury.

Antifungal Efficacy of Ganoderma lucidum and Clotrimazole for Treatment of Denture Stomatitis: A Randomized Clinical Trial

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This study tested whether Ganoderma lucidum, a medicinal mushroom used in traditional Asian medicine, could treat denture stomatitis as effectively as the standard treatment clotrimazole. Both treatments reduced pain and improved symptoms equally well over two weeks. The results suggest that Ganoderma lucidum could be a useful alternative for patients who don’t respond well to standard antifungal drugs.

Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair

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Researchers discovered that Ganoderma lucidum water extract can help convert stem cells into heart muscle cells and improve heart function after a heart attack in mice. The extract works by activating a specific cellular pathway called Wnt signaling that is important for heart development. This natural compound shows promise as a dual-action therapy that both regenerates damaged heart tissue and prevents further injury, offering a new approach to treating heart disease using natural products.

Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Ganoderma lucidum Extracts from High-Altitude Regions of Nepal

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Researchers studied a medicinal mushroom called Ganoderma lucidum (Reishi) collected from high mountains in Nepal to understand its health benefits. They tested different ways to extract beneficial compounds from the mushroom and found that using ethanol was most effective. The extracts showed strong cancer-fighting properties against cervical cancer cells and powerful antioxidant effects that may help protect the body from damage. These findings suggest this Himalayan mushroom has real therapeutic potential for treating cancer and other diseases.

Water Quality Assessment and Decolourisation of Contaminated Ex-Mining Lake Water Using Bioreactor Dye-Eating Fungus (BioDeF) System: A Real Case Study

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Researchers tested a natural solution for cleaning polluted water from an old mining lake in Malaysia. They used a special fungus called Ganoderma lucidum in a system called BioDeF that acts like a sponge to remove dirt and discoloration from contaminated water. After just 48 hours, this fungus-based system removed over 90% of the water’s brown color, offering a cheap and eco-friendly alternative to traditional water cleaning methods.

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

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Different recipes made from Ganoderma lucidum mushroom have different health benefits. This study tested two recipes in mice and found that one (PGB) was better for reducing fatigue and improving exercise performance, while the other (GBS) was better for improving sleep quality. The research shows that how you prepare and combine medicinal mushroom ingredients matters for what health benefits you get.

Evaluation of Anticancer Potential of Ganoderma lucidum on MCF-7 Breast Cancer Cells Through Genetic Transcription of Energy Metabolism

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Researchers tested extracts from Ganoderma lucidum (Reishi mushroom) against breast cancer cells in the laboratory. They found that the methanol extract was particularly effective at killing cancer cells while leaving healthy cells relatively unharmed. The mushroom works by disrupting the cancer cells’ metabolism and triggering programmed cell death, making it a promising natural treatment option that could complement conventional cancer therapies.

Research Keyword: Ganoderma lucidum