Research Keyword: galactomannan

A prospective, multicenter study of invasive fungal disease caused by molds in children and adults in Chile

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Researchers studied serious fungal infections caused by molds in Chilean hospitals and found that aspergillus was the most common culprit, affecting both children and adults. Many patients with these infections were also suffering from COVID-19, showing how serious respiratory viruses can increase the risk of fungal complications. Good news: the study found no resistance to common antifungal medications in Chile yet, though overall survival rates remain concerning at around 60% at three months.

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Photo Quiz: A cutaneous fungal infection with discordant biomarker results—a diagnostic challenge

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A woman with advanced HIV infection presented with skin sores and respiratory symptoms that were initially suspected to be a viral infection. Testing revealed she had histoplasmosis, a serious fungal infection caused by Histoplasma capsulatum that had spread throughout her body affecting her skin, lungs, and lymph nodes. While standard tests for this fungus were negative, other fungal markers and cultures eventually confirmed the diagnosis, and she was treated with antifungal medications.

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Dual fungal endocarditis in a pediatric dialysis patient: First case of Aspergillus flavus and Candida parapsilosis co-infection

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A 13-year-old boy with kidney disease requiring dialysis developed a rare dual fungal heart infection caused by two different fungi simultaneously. Doctors diagnosed the infection using heart imaging, blood tests, and tissue examination, then treated him with antifungal medications and two heart surgeries to remove infected tissue and replace a damaged heart valve. Despite the extreme rarity and severity of this condition, the patient survived, which had never been reported in children before.

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Introduction to XIV updating course of antimicrobials and infectious diseases

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Healthcare professionals gathered at a major conference in Madrid to learn about the latest advances in treating infections caused by antibiotic-resistant bacteria and other pathogens. The course highlighted new antibiotic combinations that work against previously untreatable infections, faster ways to identify infections in emergency rooms and intensive care units, and modern treatment strategies based on scientific evidence. Speakers emphasized the importance of using antibiotics wisely, using personalized medicine approaches, and collaborating between laboratory scientists and clinicians to improve patient outcomes.

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