fungemia – mycolab.ai

Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient

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A patient hospitalized with severe COVID-19 developed an unusual infection caused by a mold called Sarocladium implicatum, which typically affects plants. Due to weakened immune system from his illness and medications, the fungus spread to his bloodstream and lungs, causing persistent fever and a cavity in his lung. After molecular testing identified the fungus, he was treated with an antifungal medication called voriconazole, which successfully cured the infection.

Candida blankii: The Difficult Capture of a Fungus With Pathogenic Potential

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Candida blankii is a rare fungal pathogen that is increasingly being found in hospital patients’ bloodstreams and respiratory tracts. The organism is difficult to identify using standard laboratory tests, which can delay diagnosis and treatment. This case report describes two adult patients with C. blankii infections and highlights the challenges in identifying this emerging pathogen and its resistance to common antifungal medications.

Severe Saprochaete capitata fungemia presenting as micafungin breakthrough hepatosplenic lesions in an immunocompromised patient: case report

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A 70-year-old woman with blood cancer developed a serious fungal blood infection caused by Saprochaete capitata, a rare soil fungus, despite taking preventive antifungal medication. The infection spread to her liver and spleen, creating multiple lesions and a dangerous aneurysm. Doctors successfully treated her with a combination of three antifungal drugs, particularly voriconazole, which proved more effective than the initial preventive medication. This case highlights how rare fungi can cause severe infections in cancer patients and the importance of recognizing when standard preventive treatments are not working.

Magnusiomyces capitatus bloodstream infection in a patient with acute monocytic leukemia: A rare case report

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A 26-year-old patient with acute leukemia developed a serious fungal blood infection caused by Magnusiomyces capitatus, a rare organism found in environmental sources. The infection was confirmed using advanced molecular techniques and showed resistance to common antifungal drugs but responded to amphotericin B treatment. This case highlights how important it is for doctors to consider unusual fungi in severely immunocompromised patients and to use modern diagnostic methods for accurate identification and tailored treatment.

China’s innovative national plan to combat fungal diseases and antifungal resistance

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China has created a comprehensive national system to fight fungal infections and drug resistance. The system monitors fungal diseases across hundreds of hospitals throughout the country to track which infections are most common and which antifungal medicines are becoming less effective. Early findings show that many hospitals lack proper facilities for testing fungal infections, and some fungi are developing resistance to commonly used antifungal drugs, particularly fluconazole.

Geotrichosis Due to Magnusiomyces capitatus: A Severe Emerging Invasive Fungal Disease

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A 71-year-old man with cancer undergoing chemotherapy developed a rare and serious fungal blood infection caused by Magnusiomyces capitatus. Despite treatment with antifungal medications, the infection spread throughout his body and he died 10 days after admission. This case highlights how some fungi can resist common antifungal drugs and the importance of quickly identifying the exact type of fungus causing an infection to choose the right treatment.

Masquerading Yeast: A Case Report of Lomentospora prolificans Fungemia With a Diagnostic Twist

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This case describes a patient with blood cancer who developed a rare and deadly mold infection called Lomentospora prolificans while receiving cancer treatment. The infection was difficult to diagnose initially because the fungal structures looked similar to yeast under the microscope, and a molecular test gave a false positive result for a different fungus. Unfortunately, the infection was resistant to all available antifungal medications and the patient died.

Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient

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A 64-year-old man hospitalized with COVID-19 developed a serious fungal infection from Sarocladium implicatum, an unusual fungus rarely found in humans. The infection appeared in his bloodstream and lungs while his immune system was severely weakened by the virus and medications. Doctors identified the fungus using genetic testing and successfully treated him with voriconazole antifungal medication. This case highlights how COVID-19 patients in intensive care are vulnerable to rare opportunistic infections that require specialized laboratory testing to identify and treat.

First case of fungemia caused by a rare and pan-echinocandin resistant yeast Sporopachydermia lactativora in China

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A 37-year-old woman with leukemia developed a rare blood infection caused by a yeast called Sporopachydermia lactativora, which had never been documented to cause bloodstream infection in China before. This yeast is naturally resistant to a common class of antifungal drugs called echinocandins, making it particularly challenging to treat. However, the patient responded well to a different antifungal medication called voriconazole and fully recovered. The researchers suggest that this unusual yeast should be monitored in hospitals as it could become a more common infection in vulnerable patients.

Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review

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This study examines rare fungal infections in patients with Chronic Granulomatous Disease, a genetic disorder affecting the immune system. Researchers found that these patients develop various unusual fungal infections despite taking preventive antifungal medications. The infections are difficult to diagnose, often requiring surgical procedures, but can sometimes be cured through stem cell transplantation combined with intensive antifungal treatment.

Research Keyword: fungemia