Research Keyword: fungal pathogenesis

Five-Year Retrospective Analysis of Superficial Fungal Infections: Insights from Hospital Experience

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This study examined fungal skin infections in over 3,900 patients at a Serbian military hospital over five years. Researchers found that common fungi like Trichophyton mentagrophytes and T. rubrum caused most infections, with patterns varying by season, patient gender, and body location. Men were more likely to have foot infections while women showed more diverse fungal types. The findings suggest doctors should use more precise identification methods like MALDI-TOF testing to prescribe better treatments and help prevent recurring infections.

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Evaluating the Potential of Galactosaminogalactan as a Diagnostic Target for Invasive Aspergillosis

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Researchers developed a new test to detect invasive fungal infections caused by Aspergillus by targeting a molecule called galactosaminogalactan (GAG) on the fungus surface. The test worked very well in mice with the infection and showed better specificity than current methods. However, the test did not detect GAG in blood or other body fluids from human patients, suggesting that additional research is needed before it can be used clinically.

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Occurrence of Pathogenic and Allergenic Molds in the Outdoor and Indoor Environment of a Major Hospital and Molecular Epidemiology of Aspergillus fumigatus in Kuwait

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Researchers in Kuwait found many types of mold in and around a hospital, with some being resistant to common antifungal medications. They discovered that the same mold species were found both outdoors and in the hospital environment, suggesting patients could catch infections from the surrounding air. The study identified molds that could cause serious infections in vulnerable patients and found that about 10% of environmental samples contained drug-resistant strains that were also found in sick patients.

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