Research Keyword: fungal infection

Onychomycosis with gray-green staining caused by Fusarium solani

A 76-year-old gardener developed a gray-green discolored thumbnail that was initially thought to be a bacterial infection. Testing revealed it was actually caused by a fungus called Fusarium solani, which unusually produced dark-green colonies. The patient was successfully treated by removing the affected nail and applying an antifungal medication, demonstrating the importance of proper fungal testing for nail infections.

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Complete genome sequence analysis of Boeremia exigua, a fungal pathogen causing leaf spot disease of Panax notoginseng

Panax notoginseng, a valuable traditional Chinese medicinal plant, has been affected by a fungal leaf spot disease caused by Boeremia exigua. Researchers sequenced the complete genome of this fungal pathogen for the first time, discovering important genes responsible for its ability to infect plants, including enzymes that break down plant cell walls and proteins that help it evade plant defenses. This genetic information provides a foundation for developing better strategies to protect these valuable medicinal plants from disease.

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mGem: Sepsis and antimicrobial resistance in the context of advanced HIV disease

This review examines how serious infections (sepsis) from bacteria and fungi affect people with advanced HIV disease, particularly in hospitals. The infections have become more dangerous due to antimicrobial resistance, and many cases go undiagnosed because of limited laboratory capabilities. The paper calls for better diagnostic tools and treatment strategies tailored to resource-limited settings where most advanced HIV disease cases occur.

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Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

This case study describes three diabetic patients in Sri Lanka who developed a serious lung infection caused by a fungus called mucormycosis. The infection caused cavities in the lungs and symptoms like fever, cough, and weight loss. Two patients recovered with antifungal medication (amphotericin B) and surgery, while one patient sadly died despite receiving treatment. The study emphasizes that doctors should consider this infection in diabetic patients with unusual lung symptoms to catch it early.

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Integrated Transcriptomics–Proteomics Analysis Reveals the Response Mechanism of Morchella sextelata to Pseudodiploöspora longispora Infection

White mold disease is a major problem for morel mushroom farmers in China. Researchers identified the fungus causing this disease and studied how morel cells defend themselves. Using advanced molecular techniques, they found that morel cells respond to infection by changing their cell membranes and walls, and by activating protective proteins that fight oxidative stress. This research helps explain how the disease damages morels and could lead to developing stronger, disease-resistant mushroom varieties.

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Isolation and Characterization of Four Unreported Penicillium Species Isolated from the Freshwater Environments in Korea

Researchers in Korea discovered four species of Penicillium fungi that had never been reported in the country before, all isolated from freshwater environments. Using both traditional microscopic examination and modern DNA analysis, they confirmed these were new to Korea: P. contaminatum, P. jinfoshanicum, P. xuanhanense, and P. soppii. These findings suggest that Korean freshwater environments contain more fungal diversity than previously documented and may be important sources for studying fungi with potential medical and industrial applications.

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Prevalence of Tinea pedis in military personnel: a systematic review and meta-analysis

Athlete’s foot is a common fungal infection affecting the feet that is especially prevalent in military personnel due to their unique living and working conditions. This comprehensive analysis of 25 studies found that about 17% of military personnel worldwide have tinea pedis, with higher rates in hot and humid climates like the Americas and Australia. The infection is promoted by factors such as tight military boots, shared facilities, sweating, and poor foot hygiene. The study recommends better footwear, improved hygiene practices, and more effective diagnostic methods to reduce this health problem in military populations.

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The Effect of Aspergillus flavus on Seedling Development in Maize

Aspergillus flavus is a dangerous fungus that contaminates maize crops and produces toxic aflatoxins harmful to human and animal health. Researchers tested maize varieties to identify which are naturally resistant to this fungus using a simple laboratory method. They found significant differences in resistance among maize varieties and proposed a new evaluation system to help identify resistant varieties before they are sold to farmers, which could help reduce aflatoxin contamination in our food supply.

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Genotype-by-genotype interactions reveal transcription patterns underlying resistance responses in Norway spruce to Heterobasidion annosum s.s

Researchers studied how different spruce trees resist a wood-rotting fungus by examining which genes turn on and off during infection. They found that resistant trees quickly recognize the fungus and strengthen their cell walls, while susceptible trees have delayed responses. Interestingly, different resistant trees sometimes use different defense strategies to achieve similar protection, suggesting multiple genetic pathways can lead to the same outcome.

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Deep cutaneous fungal infection in an immunocompetent individual caused by a biological pesticide: a rare case report

A 66-year-old farmer developed a deep skin fungal infection from a biological pesticide she used for over 10 years. The pesticide contained a fungus called Purpureocillium lilacinum, which is normally harmless to healthy people but caused repeated skin lesions on her face and arms. She was successfully treated with antifungal medication (itraconazole) for three months, and her skin fully healed without returning. This is the first reported case showing that biological pesticides can pose health risks to workers who handle them regularly.

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