Research Keyword: fungal infection

Favourable outcome of Fusarium prosthetic valve endocarditis in a patient with an Ebstein anomaly

A 26-year-old woman with a congenital heart condition (Ebstein anomaly) received a replacement heart valve. Six months later, a rare fungal infection caused by Fusarium developed on the new valve, leading to lung complications. Through a combination of surgery to remove the infected valve and antifungal medications, particularly voriconazole, the patient recovered successfully. This case demonstrates that even life-threatening fungal heart infections can be treated with proper surgical intervention and targeted medication.

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Extensive and recurrent infection caused by Medicopsis romeroi in two immunocompromised patients

This case report describes two patients with weakened immune systems who developed serious fungal skin infections caused by a rare mold called Medicopsis romeroi. Both patients underwent multiple surgeries and required extended antifungal medication treatment lasting months to years. The study demonstrates that successful treatment requires a combination approach including surgical removal of infected tissue, adjustment of immunosuppressive medications, and prolonged antifungal therapy.

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Argonaute1-Dependent LtmilR2 Negatively Regulated Infection of Lasiodiplodia theobromae by Targeting a Guanine Nucleotide Exchange Factor in RAS Signalling

Scientists discovered a small RNA molecule called LtmilR2 in a fungus that causes grape canker disease. This molecule naturally suppresses the fungus’s ability to infect grapes. By delivering this molecule or similar RNA duplexes to the fungus, researchers were able to inhibit its growth and infection, suggesting a new type of biological fungicide that could protect vineyards without chemical pesticides.

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Chalkbrood Disease Caused by Ascosphaera apis in Honey Bees (Apis mellifera)—Morphological and Histological Changes in Infected Larvae

Chalkbrood is a serious fungal disease that kills honeybee larvae, caused by the fungus Ascosphaera apis. This study examined exactly how the infection progresses by infecting larvae in controlled laboratory conditions and observing them over time under a microscope. The researchers found that once infected, larvae die very quickly within 3-7 days as the fungus spreads throughout their bodies, and the fungus continues to grow even after the larvae are dead, eventually forming visible spores on the dead larvae that spread the disease to other bees in the colony.

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Trichosporon Urinary Tract Infections: A Hidden Menace Revealed

Trichosporon is a fungus that causes urinary tract infections primarily in hospitalized patients and those with weakened immune systems. This review found that Trichosporon asahii is the most common species responsible for these infections, especially in patients with prolonged hospital stays or using immunosuppressive medications. The drug voriconazole works best against this fungus, while some common antifungal medications like amphotericin B are less effective. Accurate identification using modern laboratory techniques is crucial for proper treatment.

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Mapping Histoplasma spp. in bats and cave ecosystems: evidence from midwestern Brazil

Researchers found that caves in Brazil harbor a dangerous fungus called Histoplasma that can cause a serious lung disease in humans. The study detected the fungus in soil samples from several caves and in multiple bat species living in those caves. The findings show which caves are most dangerous and emphasize the need for warning signs and protective measures for cave visitors and workers in the region.

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Prevalence of Tinea pedis in military personnel: a systematic review and meta-analysis

Athlete’s foot is a common fungal infection affecting military personnel at rates around 17% globally. Military environments create perfect conditions for this infection through close living quarters, humidity from sweat and boots, and shared facilities. The study found that regions with hot, humid climates have higher infection rates, and proper diagnosis using both microscopy and culture tests is important for accurate detection. Improved hygiene, better-designed footwear, and access to antifungal treatments can significantly reduce infection rates in military settings.

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Presence of white-nose syndrome in bats from Southern Mexico

Researchers found evidence that white-nose syndrome, a deadly fungal disease affecting bats, has reached southern Mexico. The fungus was detected in bat samples from a cave in Oaxaca, confirming earlier predictions about its spread from North America. The fungus can survive at temperatures ranging from cold to tropical heat, making it a significant threat to bat populations across diverse habitats in Mexico and beyond.

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Morphology and phylogeny reveal two new species of pestalotioid fungi associated with hawthorn in Northeast China

Researchers discovered two previously unknown fungal species living on hawthorn trees in Northeast China. Through detailed microscopic examination and genetic analysis, they identified these as Sporocadus changchunensis and S. crataegicola. Testing showed these fungi can cause disease spots on hawthorn leaves, suggesting they may pose risks to hawthorn crops. This finding helps expand our understanding of fungal species and their role in plant health.

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Unveiling Species Diversity of Plectosphaerellaceae (Sordariomycetes) Fungi Involved in Rhizome and Root Rots of Ginger in Shandong Province, China

Researchers in China identified four species of fungi causing serious rot diseases in ginger plants, including two completely new species and one previously unreported in China. These fungi were found in Shandong Province, a major ginger-growing region, and were confirmed to cause the disease through laboratory experiments. The study helps farmers understand and potentially manage these devastating ginger diseases that can destroy up to 100% of crops.

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