Research Keyword: fungal infection diagnosis

Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development

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Researchers used a special microarray technology to identify immune responses in blood samples from people infected with Candida yeast. They found that early infections trigger antibodies against certain sugar structures, while later infections produce different antibodies. Three specific sugar molecules showed promise as markers for diagnostic tests and vaccine development against dangerous yeast infections.

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Analytical Validation of a Next-Generation Sequencing Assay for the Detection of Microbial Pathogens in Human Plasma

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Researchers developed a new blood test that can detect hundreds of different fungal and bacterial infections using advanced sequencing technology. The test works by searching for pathogen DNA in blood samples and is much faster than traditional culture methods. This could help doctors quickly identify what infection a patient has and start the right treatment sooner, which is especially important for patients with weakened immune systems.

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Pan-Indian Clinical Registry of Invasive Fungal Infections Among Patients in the Intensive Care Unit: Protocol for a Multicentric Prospective Study

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Fungal infections are a serious hidden threat in hospital intensive care units, particularly for patients with weakened immune systems. This study establishes India’s first comprehensive database system to track fungal infections across 8 major medical centers nationwide. By collecting detailed information about these infections and how they respond to treatments, the research aims to help doctors diagnose and treat fungal infections faster and more effectively. The findings will guide better clinical practices and public health policies to combat these often-neglected but deadly infections.

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