fluconazole – Page 2

Enhancing antifungal stewardship: The educational and healthcare benefits of involving pharmacy students in audits

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This study involved pharmacy students in reviewing fluconazole prescriptions at two Sydney hospitals to improve antifungal medication use. The researchers found that many fluconazole prescriptions were not being used appropriately, and some patients had dangerous drug interactions. The pharmacy students gained valuable real-world experience while helping the hospitals improve their antifungal stewardship practices.

Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024

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Researchers surveyed infectious disease doctors across the United States to understand how often they test HIV patients for cryptococcal antigen, a fungal infection that can be serious. The study found that doctors don’t consistently follow recommended screening guidelines, with many uncertain about the benefits of testing. Key barriers included confusion about testing recommendations and concerns about delaying HIV treatment, suggesting that doctors need better education about the importance of early detection.

First human case of Eidernor doerrieniae colonization in a peritoneal dialysis catheter: A warning from silent contamination

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A 52-year-old man on peritoneal dialysis noticed brownish particles in his dialysis catheter. Doctors identified the particles as a rare fungus called Eidernor doerrieniae, which had never been found in humans before. Although the patient had no symptoms, doctors immediately removed the catheter and treated him with antifungal medications, which successfully cured the infection. This case shows why patients and doctors should take visible particles in dialysis catheters seriously, even when there are no obvious signs of infection.

A Case Report of Candidiasis Cellulitis in Long-Term Corticosteroid Use

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A 54-year-old man developed a serious hand infection caused by Candida albicans, a yeast that normally lives harmlessly on human skin. The infection occurred because he had been taking large doses of corticosteroid injections for 15 years to help with breathing problems, which weakened his immune system. Doctors drained the infected area and treated him with antifungal medication, and he recovered completely, highlighting the importance of recognizing fungal infections in patients on long-term steroid therapy.

Fungal peritonitis in a patient on peritoneal dialysis caused by Hyphopichia burtonii: A rare pathogen in human infection

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A woman with kidney disease on peritoneal dialysis developed an unusual fungal infection caused by Hyphopichia burtonii, a fungus typically found in spoiled food. The infection was diagnosed using advanced protein analysis technology and treated with antifungal medication after removing the dialysis catheter. Though extremely rare in humans, this case shows that unusual fungi can cause serious infections in patients with weakened immune systems and highlights the importance of considering these organisms when standard treatments don’t work.

Retrospective Analysis on the Efficacy and Adverse Effects of Antifungal Prophylaxis in Patients with Peritoneal Dialysis-Associated Peritonitis

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This study examined whether giving antifungal medications to peritoneal dialysis patients with infections could prevent fungal peritonitis. The researchers found that patients receiving antifungal prophylaxis actually had higher rates of secondary fungal infections compared to those without it. Additionally, fluconazole treatment was associated with dangerous changes in heart electrical activity, suggesting potential cardiac risks.

Fungal sepsis in a 7-month-old female: diagnosis through peripheral blood smear

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A 7-month-old girl with persistent fever that did not respond to antibiotics was found to have a yeast infection in her blood through examination of a blood sample under a microscope. This discovery was unusual because such infections are typically difficult to spot without special culture tests. After treatment with the antifungal medication fluconazole, the child recovered completely. This case shows how simple microscopy can help diagnose serious fungal infections in areas where advanced laboratory testing is not available.

Fungal peritonitis in a patient on peritoneal dialysis caused by Hyphopichia burtonii: A rare pathogen in human infection

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A woman undergoing peritoneal dialysis for kidney failure developed a serious fungal infection caused by a rare yeast called Hyphopichia burtonii. Doctors identified the infection using advanced laboratory techniques and treated her with antifungal medication after removing her dialysis catheter. She recovered well and switched to a different type of dialysis. This case highlights how unusual fungi can cause infections in patients with weakened kidney function.

The refractory nailbed ulceration caused by Candida parapsilosis after nail extraction

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An 82-year-old woman developed a stubborn ulcer on her toenail bed after having the nail surgically removed to treat an infected nail fold. Testing revealed the ulcer was caused by a yeast called Candida parapsilosis, which typically causes infections after physical trauma or injury to the skin. Treatment with an antifungal medication called fluconazole successfully healed the ulcer over three months. This is the first reported case of this specific type of infection following nail removal and highlights the importance of properly identifying the cause of chronic nail infections.

Research Keyword: fluconazole