Research Keyword: fluconazole treatment

Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024

This survey asked infectious disease doctors across the United States about their use of a simple blood test (cryptococcal antigen screening) for HIV patients. The test can detect a dangerous fungal infection weeks before symptoms appear, allowing for early treatment. However, the survey found that many doctors are not using this recommended test regularly, primarily because they are unsure about its benefits and are confused about screening guidelines.

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Feline Cryptococcosis due to Cryptococcus gattii VGII (Recently Renamed as C. deuterogattii) in an FIV-Positive Cat With Demodicosis From Manaus, Central Amazon, Brazil

A 20-month-old cat from Brazil’s Amazon region presented with nasal discharge, skin lesions, and a neck mass and was diagnosed with cryptococcosis caused by a dangerous fungus called C. deuterogattii. The cat was also infected with feline immunodeficiency virus (FIV), which weakened its immune system and made it vulnerable to the fungal infection. Treatment with the antifungal medication fluconazole successfully cured the infection within 8 weeks, and the cat made a full recovery.

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The refractory nailbed ulceration caused by Candida parapsilosis after nail extraction

An 82-year-old woman developed a stubborn wound on her toenail bed after having her nail surgically removed to treat an infection. When the wound did not heal for six months, doctors discovered it was caused by a fungus called Candida parapsilosis, which is normally found on skin but can cause infections when given the opportunity through wounds. After identifying the fungus, doctors treated her with an antifungal medication called fluconazole for three months, and her wound completely healed. This case shows the importance of testing chronic nail infections for their specific cause before performing surgery.

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