Research Keyword: evidence-based practice

Psilocybin in the real world: Regulatory, ethical, and operational challenges in Australia’s clinical landscape

Australia has approved psilocybin as a treatment for severe depression, but the rollout faces major practical challenges. Only a handful of psychiatrists are authorized to prescribe it, treatment costs over $20,000 per person, and there are no standardized training programs for therapists. The therapy can profoundly alter patients’ beliefs and worldviews, raising ethical concerns about proper support during and after treatment. The article proposes solutions including national training standards, better funding access, and stronger safeguards for vulnerable patients.

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Psychedelic-Assisted Therapy: Potential Benefits and Challenges in Mental Health Treatment

This review examines how psychedelic substances like psilocybin and MDMA, when combined with professional psychotherapy, show promise in treating difficult-to-treat mental health conditions including depression, PTSD, and anxiety. While early research suggests these substances could help in cases where conventional treatments have failed, the evidence is still preliminary and limited by small study sizes. Psychedelics appear to work by changing how the brain processes information and memories, though much more rigorous research is needed before they can be considered standard treatments.

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The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology

This article argues that ketamine therapy is commonly misunderstood as a consciousness-expanding psychedelic when it actually works through a completely different biological mechanism. The real therapeutic benefit comes from the brain’s natural reorganization in the days after treatment, not from the altered states people experience during the session itself. The authors call for medical practitioners to stop emphasizing the dissociative experience and instead focus on helping patients build healthy thought patterns during the recovery period when the brain is most ready to form new connections.

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