Research Keyword: EV biogenesis

Things you wanted to know about fungal extracellular vesicles (but were afraid to ask)

Fungal extracellular vesicles are tiny particles released by fungal cells that play important roles in how fungi cause disease and how our immune system responds. These particles can either help fight infections or make them worse depending on the type of fungus and conditions involved. Scientists are discovering that these vesicles could potentially be used as vaccines and may explain why some antifungal drugs stop working.

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Growth conditions shape the proteome and diversity of Neurospora crassa extracellular vesicles

Scientists studied tiny particles called extracellular vesicles released by a common fungus (Neurospora crassa) under different growth conditions. Using advanced techniques, they identified hundreds of proteins within these vesicles and found that what the fungus eats and how long it grows significantly changes the types and amounts of proteins the vesicles carry. The findings reveal that fungi release different types of vesicles than previously thought, expanding our understanding of how cells communicate and transport materials.

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