Research Keyword: epidemiology

Addressing Critical Fungal Pathogens Under a One Health Perspective: Key Insights from the Portuguese Association of Medical Mycology

Four dangerous fungal species pose growing threats to human health worldwide, especially for people with weakened immune systems. Portugal’s medical experts have reviewed the current situation, finding these fungi increasingly resistant to treatment, present in hospitals and the environment, and occasionally spreading from animals to people. The review emphasizes the need for better testing, coordinated tracking systems, and approaches that consider human, animal, and environmental health together to combat this emerging crisis.

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More than ten years without changes in the prevalence of adverse food reactions among Mexican adults: Comparison of two cross-sectional surveys

Researchers compared food allergy rates in Mexico between 2012-2013 and 2023-2024, finding that about 19% of adults reported adverse food reactions in both periods. Surprisingly, unlike many other countries that have seen increases in food allergies, the prevalence in Mexico remained stable over the 11-year period. Women and people with allergic skin conditions or hay fever were more likely to experience food reactions, while those aged 25-50 had lower risk.

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Mapping Histoplasma spp. in bats and cave ecosystems: evidence from midwestern Brazil

Researchers studied caves in midwestern Brazil and found that a fungal pathogen called Histoplasma, which causes a serious lung disease called histoplasmosis, is present in cave environments and in bats. They developed a quick DNA test to detect this fungus in cave soil samples and bat tissue samples. The study identified specific caves with high levels of the fungus, which could help warn visitors and cave explorers about the risk of infection.

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Epidemiology and outcomes of Candida-associated osteoarticular infections: A multicentre retrospective study from Turkey

This study examined 73 patients in Turkey who developed bone and joint infections caused by Candida fungi over ten years. The researchers found that diabetes was very common among patients and made recovery harder, while surgery to clean out infected tissue significantly improved outcomes. Importantly, they discovered resistance to common antifungal medications was higher in certain Candida species compared to others.

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Knowledge, attitude, and practice on mushroom poisoning among residents of Jilin province

This study surveyed over 500 residents in Jilin Province about their understanding of mushroom poisoning risks. The results showed that most people had limited knowledge about toxic mushrooms, though many held positive attitudes about food safety. However, knowing about the dangers did not always translate into safer behaviors. The research suggests that better education, especially for rural residents, could help prevent dangerous mushroom poisoning incidents.

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Breakthrough Invasive Mould Infections Under Posaconazole Prophylaxis in Patients With Haematologic Malignancies: A Case–Control Study

This study examined cases where patients receiving posaconazole to prevent fungal infections still developed serious mould infections despite the medication. Researchers compared 29 patients who developed these breakthrough infections with 46 control patients who did not. They found that over half of patients with breakthrough infections died, compared to only 20% of controls, and that surgical treatment significantly improved survival for certain types of fungal infections.

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The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies

Climate change is making it easier for dangerous fungi to grow and spread to new areas where people have never encountered them before. As temperatures rise and weather becomes more extreme, fungi are becoming resistant to our medicines, especially antifungal drugs used in both farming and hospitals. People living in poverty, displaced by natural disasters, and those without good healthcare access are most vulnerable to these infections. We need to act quickly by developing new treatments, improving diagnosis, reducing agricultural fungicide use, and strengthening healthcare systems in vulnerable communities.

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Climate Change, Natural Disasters, and Cutaneous Fungal Infections

Climate change and natural disasters are creating conditions that allow fungal infections to spread more easily and affect people in new ways. Warmer temperatures help fungi adapt to infect humans, while floods, earthquakes, and hurricanes expose people to fungal spores and create wounds through which infections can enter. Doctors need to be alert for unusual fungal infections after disasters, especially since some of these infections can cause serious complications and resist common treatments.

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Association of mushroom consumption with all-cause and cause-specific mortality among American adults: prospective cohort study findings from NHANES III

This study followed over 15,000 American adults for nearly 20 years and found that people who ate mushrooms had a lower risk of dying from any cause compared to those who didn’t eat mushrooms. The more mushrooms people ate, the greater the benefit. Replacing red or processed meat with mushrooms was associated with even greater longevity benefits. Mushrooms’ beneficial effects likely come from their high antioxidant content, particularly compounds called ergothioneine and glutathione.

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Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024

This survey asked infectious disease doctors across the United States about their use of a simple blood test (cryptococcal antigen screening) for HIV patients. The test can detect a dangerous fungal infection weeks before symptoms appear, allowing for early treatment. However, the survey found that many doctors are not using this recommended test regularly, primarily because they are unsure about its benefits and are confused about screening guidelines.

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