Research Keyword: eosinophilic inflammation

Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

Scientists studied two fungi that infect plants to see if they could cause asthma-like reactions in mice. They found that these fungi triggered inflammatory responses and produced antibodies similar to other known allergens. While not as potent as ovalbumin (a common test allergen), these plant-infecting fungi showed potential as respiratory allergens that may affect people exposed to them.

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Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

Researchers studied two types of plant fungi that infect common vegetables and plants to determine if they could cause asthma in mice. They found that both organisms triggered immune responses similar to those caused by known allergens, producing inflammation and asthma-like symptoms. Although their effects were weaker than the reference allergen ovalbumin, both fungi showed significant potential as respiratory allergens. This research suggests these plant parasites should be recognized as possible triggers for asthma and allergic reactions in people.

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