Research Keyword: endothelial dysfunction

Glyoxalase 1 Inducer, trans-Resveratrol and Hesperetin–Dietary Supplement with Multi-Modal Health Benefits

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A dietary supplement combining trans-resveratrol and hesperetin activates a cellular defense mechanism called Nrf2, which increases production of an enzyme (Glo1) that helps eliminate harmful byproducts of sugar metabolism. This supplement improved multiple aspects of health in studies, including better blood sugar control, reduced inflammation, and improved liver function. The combination works better than either ingredient alone, and the trans form of resveratrol is much more effective than the cis form.

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Special Issue: Marine-Derived Compounds Applied in Cardiovascular Disease

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This collection of studies explores how compounds from ocean sources like seaweed, fish, shrimp, and microalgae can help protect heart health and prevent cardiovascular diseases. Researchers examined various marine ingredients and found they can reduce inflammation, lower cholesterol, reduce blood pressure, and prevent blood clots. The findings suggest that marine-derived products could become safer, more affordable alternatives or complements to current heart disease medications while supporting sustainable ocean resource use.

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From Microbes to Myocardium: A Comprehensive Review of the Impact of the Gut-Brain Axis on Cardiovascular Disease

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Your gut bacteria play a surprising role in heart health through a communication network called the gut-brain axis. When the balance of gut bacteria is disrupted (dysbiosis), it can lead to heart disease, high blood pressure, and clogged arteries. Beneficial bacteria produce helpful compounds like short-chain fatty acids that reduce inflammation and protect blood vessels, while harmful bacteria produce compounds that increase heart disease risk. Simple interventions like eating more fiber, taking probiotics, managing stress, and exercising can help maintain a healthy gut microbiome and improve heart health.

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Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

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This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

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Splenic Infarct: A Rare Complication of Infectious Mononucleosis in a Monospot-Negative Patient

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A 21-year-old woman came to the hospital with fever, jaundice, and abdominal pain that persisted despite antibiotics. Although her monospot test for mononucleosis came back negative, blood tests for a virus called Epstein-Barr Virus (EBV) confirmed she had infectious mononucleosis. Imaging scans revealed multiple areas of dead tissue (infarcts) in her spleen caused by blocked blood vessels. She recovered well with rest and supportive care, highlighting how mononucleosis can sometimes cause serious complications even when the initial screening test is negative.

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