endoplasmic reticulum

Antifungal efficacy and mechanisms of Bacillus licheniformis BL06 against Ceratocystis fimbriata

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Researchers discovered that a beneficial bacterium called Bacillus licheniformis BL06 can effectively prevent sweet potato black rot, a fungal disease that causes major crop losses worldwide. When applied to sweet potatoes, this bacterium reduces disease damage by interfering with the fungus’s ability to grow, form spores, and survive. The study reveals that the bacterium works by disrupting the fungus’s cell structure and energy production, making it a promising natural alternative to chemical fungicides.

Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease

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Scientists studied how Bcl-2 proteins might protect the brain from Alzheimer’s disease by controlling calcium levels in nerve cells. They injected modified Bcl-2 proteins into the brains of mice engineered to develop Alzheimer’s symptoms and found that these proteins helped preserve the connections between nerve cells and reduced harmful amyloid plaque buildup. A special version of Bcl-2 that worked primarily on one type of calcium channel was surprisingly most effective at reducing amyloid plaques, suggesting this specific mechanism could be important for treating Alzheimer’s disease.

Novel endornaviruses infecting Phytophthora cactorum that attenuate vegetative growth, promote sporangia formation and confer hypervirulence to the host oomycete

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Researchers discovered two new viruses infecting a plant-damaging organism called Phytophthora cactorum. When these viruses are present, the organism grows more slowly but becomes more aggressive at infecting plants. The viruses attach to special membranes inside cells and depend on cholesterol-like compounds for their replication. Scientists were able to remove the viruses from infected strains using specialized techniques, allowing them to compare infected and virus-free versions of the organism.

Research Keyword: endoplasmic reticulum

Antifungal efficacy and mechanisms of Bacillus licheniformis BL06 against Ceratocystis fimbriata

Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease

Novel endornaviruses infecting Phytophthora cactorum that attenuate vegetative growth, promote sporangia formation and confer hypervirulence to the host oomycete