Research Keyword: endophthalmitis

Endogenous Endophthalmitis: An underestimated serious complication in patients with disseminated fusariosis

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An 18-year-old cancer patient undergoing chemotherapy developed a serious infection with Fusarium, a mold that spread throughout his body including to his eyes, causing vision problems. Doctors treated him with a combination of antifungal medications given both systemically and directly injected into his eyes. Although the infection was controlled and his life was saved, he lost most of his vision in both eyes but was able to keep them rather than requiring removal.

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Efficacy of Rezafungin on Candida albicans Endophthalmitis in a Rabbit Model

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Researchers tested a new antifungal medication called rezafungin to treat a serious eye infection caused by the fungus Candida albicans. Using rabbit models, they found that rezafungin was much more effective than two other antifungal drugs at clearing the infection from the eye and preventing damage to vision. The drug’s ability to work for longer periods with less frequent dosing makes it a promising candidate for treating this devastating infection in patients.

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Efficacy of Rezafungin on Candida albicans Endophthalmitis in a Rabbit Model

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Researchers tested a new antifungal drug called rezafungin against a serious eye infection caused by Candida fungus in rabbits. Rezafungin performed much better than two other commonly used antifungal drugs, completely eliminating the fungus from the eye while preventing infection-related damage. The drug’s ability to be given weekly instead of daily makes it more practical for treating patients with severe fungal eye infections.

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Endogenous Endophthalmitis: An underestimated serious complication in patients with disseminated fusariosis

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An 18-year-old boy with acute leukemia developed a serious fungal infection caused by Fusarium mold that spread throughout his body, including to both eyes. Despite receiving intensive antifungal medications injected directly into his eyes along with systemic treatment, he lost his vision. However, through aggressive combined therapy, doctors were able to save both eyes and continue his cancer treatment successfully.

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Taxonomic revision of Bisifusarium (Nectriaceae)

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Scientists have identified and formally named 8 new species of Bisifusarium, a genus of fungi found in cheese, soil, and some human infections. Using genetic analysis and careful observation of fungal structures, researchers studied 116 fungal samples collected from around the world. This work more than doubled the known number of Bisifusarium species from 16 to over 24, providing clearer identification methods for future research in food science and medicine.

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Cryptococcal endophthalmitis in a patient with malignancy: A case report and literature review

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A 50-year-old woman with advanced lung cancer developed a rare fungal eye infection caused by Cryptococcus neoformans, resulting in blurred vision. Doctors diagnosed this through eye surgery and fluid analysis, then treated her with strong antifungal medications both injected into the eye and given systemically. After 10 months of treatment, her vision significantly improved, showing that early detection and aggressive antifungal therapy are critical for preventing blindness from this rare infection.

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