Research Keyword: Endocytosis

Current status and future prospects of microalgae-based degradation of spent lubricant oil hydrocarbon towards environmental sustainability: a mini review and bibliometric analysis

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Spent oil waste from cars and industries is a major environmental problem that traditional cleanup methods struggle to handle. This review shows that microalgae, tiny organisms that are already used for various purposes, can effectively break down the harmful chemicals in used oil. A bibliometric analysis reveals that scientists worldwide, especially in China, are increasingly researching this promising green solution to clean up oil pollution in soil and water.

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The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans

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Researchers studied three important protein switches (Rab GTPases) in a fungus that causes cabbage wilt disease. By deleting these proteins one at a time, they found that each plays a critical role in fungal growth, spore production, and the ability to infect plants. The findings suggest that targeting these proteins could be a strategy to control the devastating cabbage wilt disease.

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Fungal pathogens and symbionts: Living off the fat of the land

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Certain fungi that live exclusively in or on hosts have evolved a clever survival strategy: they stopped making their own fatty acids and instead steal them from their hosts. This includes fungi that cause pneumonia in immunocompromised patients, yeasts on skin, and beneficial fungi that help plants absorb nutrients from soil. By examining how these fungi scavenge fatty acids from their hosts, scientists hope to develop better treatments and diagnostic tools for fungal infections.

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Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

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Researchers developed tiny nanoparticle carriers coated with a fungal enzyme that helps them cross the protective barrier around the brain. These particles were loaded with an antifungal drug to treat brain infections caused by Cryptococcus neoformans. In laboratory tests, the Mpr1-coated particles successfully penetrated the blood-brain barrier better than regular nanoparticles and were more effective at killing the fungal cells.

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The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans

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Scientists studied three proteins (Rab GTPases) in a fungal pathogen that causes cabbage wilt disease. These proteins act like traffic controllers, directing materials within fungal cells to support growth and disease spread. By removing these genes one at a time, researchers found that all three proteins are essential for the fungus to infect plants, produce spores, and survive stress conditions. This research could eventually help develop new ways to control this destructive crop disease.

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The Slit–Robo signalling pathway in nervous system development: a comparative perspective from vertebrates and invertebrates

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This review explains how growing nerve fibers find their way in the developing brain and spinal cord using special signalling molecules called Slit and Robo. These molecules work together like a navigation system, with Slit acting as a ‘stop’ signal secreted from midline structures and Robo receptors on growing axons receiving these signals. The same system is used by flies, worms, and humans, showing that this guidance mechanism is an ancient and essential part of nervous system development.

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