Research Keyword: electrophysiology

Neural mechanisms underlying psilocybin’s therapeutic potential – the need for preclinical in vivo electrophysiology

mycolabadmin

Psilocybin, the active compound in magic mushrooms, shows promise for treating depression and other mental health conditions. This review examines how psilocybin works in the brain, particularly by affecting brain regions involved in self-reflection and emotion regulation. The authors argue that new brain recording techniques are needed to fully understand how psilocybin produces its beneficial effects, which could help improve treatments for people with severe depression.

Read More »

Organic electro-scattering antenna: Wireless and multisite probing of electrical potentials with high spatial resolution

mycolabadmin

Researchers have developed tiny organic antennas that can wirelessly detect electrical signals in liquid environments with remarkable precision. These antennas use light scattering to monitor electrical activity and can be densely packed together to simultaneously measure thousands of signals from different locations. The technology could revolutionize how scientists study heart cells, nerve cells, and other bioelectrical phenomena, potentially enabling new medical diagnostic tools and treatments.

Read More »

GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory

mycolabadmin

Researchers studied how a specific brain protein called GluN2B affects addiction memories from cocaine use. They found that removing this protein reduced the formation of ‘silent synapses’ – immature brain connections created by cocaine – and weakened drug-related memories. However, this also unexpectedly made mice more active, suggesting that GluN2B normally helps control both addiction memory and activity levels. The findings provide new insights into how addiction memories form and suggest potential ways to treat addiction.

Read More »

The cellular architecture of memory modules in Drosophila supports stochastic input integration

mycolabadmin

Scientists created a detailed computer model of a memory-processing neuron in the fruit fly brain to understand how memories are stored and recalled. The study found that the neuron’s design allows it to store many different memories using random connections from input neurons, similar to how a brain might encode multiple learned experiences. This research reveals that memories can be efficiently stored without requiring precise positioning of individual neural connections, suggesting the brain uses flexibility and randomness as computational strategies.

Read More »

The Role of Acid-Sensing Ion Channel 1A (ASIC1A) in the Behavioral and Synaptic Effects of Oxycodone and Other Opioids

mycolabadmin

This study examines how a specific type of brain channel called ASIC1A affects how the brain responds to opioid drugs like oxycodone and morphine. Researchers found that mice without this channel showed stronger attraction to opioid-paired locations and had unusual changes in brain connections related to opioid use. The findings suggest that targeting ASIC1A could potentially be a new way to treat opioid addiction by reducing the brain’s sensitivity to these drugs.

Read More »

Detection of electrical signals in fungal mycelia in response to external stimuli

mycolabadmin

Researchers developed a new method to detect and measure electrical signals produced by fungal mycelium using specialized circuit boards and advanced analysis techniques. The study found that fungi generate electrical activity that correlates with their growth, which can be altered by treating them with different chemicals. This discovery suggests that fungi may use electrical signals to communicate and adapt to their environment, similar to how animals and plants use electrical signaling. The new method provides a foundation for better understanding how fungi communicate within their networked mycelial systems.

Read More »
Scroll to Top