Research Keyword: electron microscopy

Deciphering the formation of biogenic nanoparticles and their protein corona: State-of-the-art and analytical challenges

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Scientists have developed environmentally friendly methods to create tiny metal particles (nanoparticles) using living organisms like bacteria, fungi, and plants instead of toxic chemicals. These bioengineered nanoparticles are coated with natural biological molecules that make them safer and more stable. This review explains how these particles are made, what analytical tools scientists use to study them, and their potential uses in medicine, environmental cleanup, and agriculture.

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Lomasomes and Other Fungal Plasma Membrane Macroinvaginations Have a Tubular and Lamellar Genesis

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Scientists studied mushroom cells to understand structures called lomasomes that form at the cell membrane surface. Using advanced microscopy techniques, they discovered these structures are made of tiny tubes and layers that can fold and swell into different shapes. These findings help explain how fungal cells that decompose wood organize their membranes and may be involved in how cells take in materials from their surroundings.

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Intracellular accommodation of bacteria, fungi, and oomycetes by plants analyzed using transmission electron microscopy

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Scientists used high-powered electron microscopes to examine how plants host different microorganisms inside their cells. They found that whether the microorganism is a helpful nitrogen-fixing bacterium, a nutrient-exchanging fungus, or a disease-causing oomycete, plants always separate it from the rest of the cell with a special membrane. This study reveals fundamental similarities in how plants accommodate different types of microorganisms, despite the very different outcomes for the plant.

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GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory

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Researchers studied how a specific brain protein called GluN2B affects addiction memories from cocaine use. They found that removing this protein reduced the formation of ‘silent synapses’ – immature brain connections created by cocaine – and weakened drug-related memories. However, this also unexpectedly made mice more active, suggesting that GluN2B normally helps control both addiction memory and activity levels. The findings provide new insights into how addiction memories form and suggest potential ways to treat addiction.

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