dysbiosis – Page 4

Potential Protective Role of Amphibian Skin Bacteria Against Water Mold Saprolegnia spp.

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Frogs have helpful bacteria living on their skin that can fight dangerous water molds called Saprolegnia. Scientists discovered that different types of bacteria, especially Bacillus species, can prevent these molds from growing. The study found that frogs from polluted or salty water actually had bacteria that were better at fighting the mold, likely because harsh conditions helped tougher bacteria survive. These protective bacteria might explain why adult frogs can resist these infections better than tadpoles or eggs.

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

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Natural plant and organism sugars called polysaccharides can improve your gut health by feeding beneficial bacteria and strengthening your intestinal barrier. These compounds help prevent diseases like obesity, diabetes, and inflammatory bowel disease by changing the types of bacteria in your gut and producing helpful substances. Polysaccharides come from common foods like mushrooms, seaweed, berries, and vegetables, making them potential natural treatments for various health conditions.

The Effect of Topical Ketoconazole and Topical Miconazole Nitrate in Modulating the Skin Microbiome and Mycobiome of Patients With Tinea Pedis

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This study examined how two common antifungal creams (ketoconazole and miconazole) affect the complex community of bacteria and fungi living on the skin of people with athlete’s foot. Both treatments effectively reduced the harmful fungus causing the infection and improved symptoms, with ketoconazole working slightly faster. However, the researchers found that while these treatments reduced the disease-causing fungus, the skin’s normal microbial community did not fully recover to a healthy state, particularly in the spaces between the toes.

Potential relationship between gut microbiota and animal diarrhea: a systematic review

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This review explains how the trillions of microorganisms living in animal intestines are crucial for health and digestion. When these microbial communities become imbalanced, animals develop diarrhea, which is a major problem in farming causing economic losses and animal suffering. The review shows that adding beneficial bacteria (probiotics) and their food sources (prebiotics) to animal diets can restore balance and prevent diarrhea, offering practical solutions to reduce the need for antibiotics.

The ATO gene family governs Candida albicans colonization in the dysbiotic gastrointestinal tract

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This study shows that the fungus Candida albicans uses a family of protein transporters called ATO to absorb acetate, a fatty acid produced by gut bacteria. When mice were treated with antibiotics that killed their beneficial bacteria, C. albicans could colonize their guts better if it had working ATO transporters. The research reveals that fungi have evolved special systems to take advantage of nutrients left behind when the normal gut bacteria are disrupted, which helps explain why fungal infections are more common after antibiotic use.

Effects of Short-Chain Fatty Acid Combinations Relevant to the Healthy and Dysbiotic Gut upon Candida albicans

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Short-chain fatty acids produced by healthy gut bacteria appear to slow the growth and reduce the invasive characteristics of Candida albicans, a fungus that normally lives harmlessly in the gut but can cause infections when the microbiota is disrupted by antibiotics. This study tested whether healthy gut SCFA levels inhibit Candida more effectively than dysbiotic levels and found that the healthy SCFA mix was somewhat more effective at preventing fungal hyphal formation, which is important for tissue invasion. However, different Candida strains responded differently to the SCFAs, suggesting that individual variation affects how protective these bacterial metabolites can be.

Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application

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This review explores how probiotics (beneficial live bacteria) can help treat inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. Probiotics work by restoring healthy bacteria balance in the gut, strengthening the intestinal barrier, and calming the immune system’s inflammatory response. While more research is needed, particularly for Crohn’s disease, probiotics show promise as a safe, long-term treatment option that can complement standard medications and improve patients’ quality of life.

Human Gut Microbiome: A Connecting Organ Between Nutrition, Metabolism, and Health

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Your gut bacteria function like an extra organ, helping digest food and producing important compounds that affect your whole body. The type of bacteria in your gut depends on diet, delivery method at birth, and antibiotics you’ve taken. Eating more fiber and taking certain probiotics can improve your bacterial balance and help prevent diseases like diabetes, obesity, and heart problems. This suggests that managing your gut microbiome through diet might be just as important as taking traditional medicines for staying healthy.

Inhibition of RNase to Attenuate Fungal-Manipulated Rhizosphere Microbiome and Diseases

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Fusarium fungi cause major crop diseases by using a protein called Fg12 that kills helpful bacteria in plant roots, making it easier for the fungus to infect crops. Scientists discovered that a compound called GMP blocks Fg12’s harmful activity and restores beneficial bacteria, reducing disease symptoms in soybeans and alfalfa by 47-75%. This discovery offers a new chemical strategy to protect crops from fungal infections by disarming this key fungal weapon.

The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy

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Sepsis can cause brain dysfunction called sepsis-associated encephalopathy, leading to memory problems and confusion in about one-third to two-thirds of sepsis patients. The bacteria in your gut communicate with your brain through multiple pathways, and when sepsis disrupts this communication, it causes harmful inflammation in the brain. Treatments like probiotics and transplanting healthy gut bacteria from donors show promise in animal studies and early human trials for improving memory and cognitive function after sepsis.

Research Keyword: dysbiosis