Research Keyword: dysbiosis

Maternal Euglena gracilis supplementation alters sow and piglet gut microbiota, reduces diarrhea incidence, and enhances piglet growth

This study examined how feeding sows a supplement called Euglena gracilis (an algae-derived prebiotic) affected the gut bacteria of both the sows and their piglets. Piglets born to supplemented sows weighed more at weaning and had fewer cases of diarrhea during the nursing period. The supplement changed the types of bacteria in both the sows’ and piglets’ guts in beneficial ways, promoting healthier and more stable gut communities that supported better growth and digestive health.

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Microbiota-based interventions for autism spectrum disorder: a systematic review of efficacy and clinical potential

This comprehensive review examines how modifications to gut bacteria through probiotics, prebiotics, synbiotics, and fecal transplants can help children with autism. The research found that while all these treatments showed some promise, fecal microbiota transplantation (FMT) produced the most consistent improvements in both autism-related behaviors and digestive symptoms. These microbiota-based approaches work through the gut-brain connection and were generally safe, making them potentially valuable additions to autism management strategies.

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Nutritional strategies in supporting immune checkpoint inhibitor, PI3K inhibitor, and tyrosine kinase inhibitor cancer therapies

This review examines how nutrition and food-based interventions can improve cancer treatment outcomes for patients receiving targeted cancer therapies. A Mediterranean-style diet with plenty of fiber (30-50g daily) appears beneficial for patients on immune checkpoint inhibitor therapies by promoting healthy gut bacteria that support immune function. The review also discusses promising research on fermented foods, specific bacterial supplements, mushroom extracts, and fasting approaches as complementary strategies to enhance cancer treatment effectiveness while reducing side effects.

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Unveiling roles of beneficial gut bacteria and optimal diets for health

Your gut bacteria are tiny living organisms that help digest food, support your immune system, and influence your overall health. Eating foods rich in fiber, fermented products like yogurt and kimchi, and colorful fruits and vegetables helps grow these beneficial bacteria. When your gut bacteria become unbalanced, it can lead to inflammation and various diseases, but eating the right foods can restore balance and improve your health.

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The Effect of 2′-Fucosyllactose on Gut Health in Aged Mice

This research shows that 2′-fucosyllactose, a natural compound found in breast milk, can significantly improve gut health in older mice. The treatment strengthened the intestinal barrier, reduced harmful inflammation, and increased beneficial bacteria populations. These findings suggest that 2′-FL could be developed as a food supplement to help older people maintain better digestive and immune health.

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Regulatory effects of Poria cocos polysaccharides on gut microbiota and metabolites: evaluation of prebiotic potential

Poria cocos is a medicinal mushroom commonly used in Asian cuisine and traditional medicine. This study found that its polysaccharides act as prebiotics by feeding beneficial gut bacteria like Lactobacillus and Bifidobacterium while reducing harmful bacteria. The fermentation produces beneficial compounds called short-chain fatty acids that support digestive health and may help prevent diseases like obesity and inflammation.

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Gut-Brain Axis in Obesity: How Dietary Patterns Influence Psychological Well-Being and Metabolic Health

This review explains how our diet affects both our gut bacteria and our mental health through the gut-brain axis, a communication system between our digestive system and brain. Mediterranean diets rich in fiber and healthy foods support beneficial bacteria and mental well-being, while Western diets high in processed foods harm gut health and increase obesity risk. Emotional eating driven by stress and depression worsens obesity, but targeted dietary interventions with prebiotics, probiotics, and fiber can help restore balance and improve both physical and mental health.

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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)

Researchers studied a kombucha tea drink enriched with fiber from chicory root in healthy adults over six weeks. The study found that people who consumed the fiber-enriched kombucha had lower triglyceride levels (blood fats) and beneficial changes in their gut bacteria, particularly an increase in Bifidobacterium, a bacteria known to support digestive health. These results suggest that this type of kombucha could be beneficial for metabolic and gut health, though more research is needed to confirm these benefits.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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Dietary live microbe intake and its association with Parkinson’s disease in American adults: an NHANES analysis (1999–2018)

This study found that eating more foods rich in live microbes—like fermented products (yogurt, kimchi) and fresh fruits and vegetables—is associated with lower rates of Parkinson’s disease in American adults. The protective effect was strongest in people without obesity. The live microbes appear to work by maintaining a healthy gut environment, reducing inflammation, and protecting nerve cells from damage. This suggests that regular consumption of microbe-rich foods from nature might be a simple, inexpensive way to help prevent or slow Parkinson’s disease.

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