Research Keyword: drug-induced liver injury

Ganoderma lingzhi (Reishi Mushroom)-Induced Acute Liver Injury in the Setting of Alcohol Use: A Case Report and Review of the Literature

mycolabadmin

A 47-year-old man developed severe liver inflammation after consuming Reishi mushroom powder while drinking large amounts of vodka over three days. Although Reishi mushrooms are commonly promoted as healthy supplements, in this case the combination with alcohol caused his liver enzymes to spike dangerously high. The patient recovered after hospital treatment, but the case highlights that even natural supplements can be harmful, especially when combined with alcohol. This raises concerns that more research is needed on how mushroom supplements interact with other substances people consume.

Read More »

Educational Case: Acetaminophen hepatotoxicity: Pathophysiology and evaluation of acute liver failure

mycolabadmin

This educational case describes how acetaminophen overdose causes severe liver damage leading to acute liver failure. The toxic form of acetaminophen damages liver cell mitochondria and causes widespread cell death, particularly in the center of liver lobules. Treatment with N-acetylcysteine within 24 hours of overdose significantly improves outcomes, though severe cases require liver transplantation.

Read More »

Herbal Supplement-Induced Liver Injury: A Case Report

mycolabadmin

A 45-year-old woman developed severe liver injury after drinking an herbal tea containing multiple ingredients, including reishi mushroom and aloe vera. Her liver function gradually improved after she stopped drinking the tea, with complete recovery within three months. This case demonstrates that herbal supplements, often perceived as safe, can cause serious liver damage and should be investigated when patients develop unexplained liver problems.

Read More »

A Rare Case of Methyldopa-Induced Hepatitis

mycolabadmin

A 31-year-old woman developed severe liver inflammation (hepatitis) six weeks after starting methyldopa, a common blood pressure medication. After stopping the drug, her liver function returned to normal without needing steroids or other intensive treatments. This case reminds doctors that even commonly used, safe medications can rarely cause serious liver problems and should be considered when patients develop unexplained liver inflammation.

Read More »
Scroll to Top