Research Keyword: dose-response relationship

The therapeutic potential of microdosing psychedelics in depression

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This review examines whether taking very small doses of psychedelic drugs like LSD and psilocybin might help treat depression. While users report benefits and some studies show subtle positive effects on mood and thinking, scientists have not yet confirmed whether microdosing actually works as a depression treatment. More research with depressed patients is needed to understand if this approach is truly helpful and safe for regular use.

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Enhancing Pearl oyster mushroom (Pleurotus ostreatus) performance by evaluating the influence of potassium humate and wheat straw on yield and biochemical attributes

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This study examined how adding potassium humate (a natural organic compound) to wheat straw substrate affects the growth and quality of oyster mushrooms. Researchers tested seven different amounts of potassium humate over two growing seasons and found that a moderate amount (0.5 g per 500 g straw) produced the best results, increasing both mushroom yield and nutritional value including vitamin C and beneficial sugars. Interestingly, using more potassium humate was not better, showing that balanced application is more effective than maximum supplementation for optimal mushroom production.

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Correlation between Vegetable and Fruit Intake and Cognitive Function in Older Adults: A Cross-Sectional Study in Chongqing, China

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This study examined how eating different types of fruits and vegetables affects brain health in older adults in Chongqing, China. Researchers found that higher fruit intake and eating more root vegetables (like carrots and turnips) were associated with better cognitive function and lower risk of mild cognitive impairment. Some vegetables like tomatoes and peppers also showed protective benefits, while leafy greens did not show a significant effect. The findings suggest that encouraging older adults to eat more fruits and certain vegetables could help prevent memory problems and cognitive decline.

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Adaptive Responses in High-Radiation Environments: Insights From Chernobyl Wildlife and Ramsar Residents

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Animals and people living in highly radioactive areas have developed natural adaptations to survive and thrive despite dangerous radiation levels. Frogs in Chernobyl have evolved darker skin that helps protect against radiation, while residents of Ramsar, Iran have developed enhanced DNA repair abilities over generations. These discoveries challenge traditional beliefs about radiation dangers and suggest that life can adapt to extreme environmental stressors in unexpected ways.

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Efficacy of SCY-247, a Second-generation Triterpenoid Antifungal, in Three Murine Models of Invasive Fungal Infections

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Researchers tested a new antifungal drug called SCY-247 in mice to treat serious fungal infections. The drug was given orally and showed strong effectiveness against common fungal infections caused by Candida and Rhizopus species, including strains resistant to current treatments. Higher doses of the drug produced better results, and the drug effectively concentrated in the organs most affected by fungal infections.

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