Research Keyword: disseminated disease

Mediastinal cryptococcoma as part of disseminated cryptococcosis in HIV-negative pregnant woman with Myasthenia Gravis: Autopsy case report

mycolabadmin

A 29-year-old pregnant woman with myasthenia gravis, a condition requiring long-term immune-suppressing medications, died from a widespread fungal infection caused by Cryptococcus. Despite being HIV-negative, her weakened immune system made her vulnerable to this serious infection. An autopsy revealed the infection had spread throughout her body, including her heart, brain, lungs, and kidneys. This case highlights how fungal infections like cryptococcosis can affect people without HIV when their immune systems are compromised by other conditions or medications.

Read More »

Clinical Significance and Therapeutic Challenges of Scedosporium spp. and Lomentospora prolificans Isolates in a Single-Center Cohort of Lung Transplant Recipients

mycolabadmin

This study examined rare but serious fungal infections caused by Scedosporium and Lomentospora in lung transplant patients. Of 576 transplant recipients, 11 (2%) developed these infections, which are difficult to treat due to natural resistance to most antifungal medications. The infection type greatly influenced outcomes, with disseminated Lomentospora infections causing 100% mortality despite treatment. The research highlights the urgent need for new diagnostic methods and more effective antifungal drugs to combat these emerging pathogens.

Read More »

Frequency, Interval, and Patient Factors Associated With Recurrence of Disseminated Cutaneous Coccidioidomycosis

mycolabadmin

This study looked at how often a serious fungal skin infection called coccidioidomycosis comes back after treatment. Researchers found that about 25% of patients experienced at least one recurrence after stopping antifungal medications, with the average time before it returned being 14 months. Some patients had multiple recurrences, and most of the time the infection returned to the same location on the body.

Read More »

Histoplasma capsulatum as a cause for prolonged pulmonary illness in an immunocompetent returning traveller from Bangladesh

mycolabadmin

A 57-year-old man returning from Bangladesh developed a severe lung infection that lasted several weeks and required hospitalization with breathing support. Doctors initially thought he had tuberculosis or bacterial pneumonia, but standard tests came back negative. Advanced fungal testing eventually identified the cause as histoplasmosis, a fungal infection he likely caught while supervising construction work. After treatment with antifungal medications, the patient recovered and was discharged to continue medication at home for a year.

Read More »
Scroll to Top