Research Keyword: diagnostic methods

Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024

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Researchers surveyed infectious disease doctors across the United States to understand how often they test HIV patients for cryptococcal antigen, a fungal infection that can be serious. The study found that doctors don’t consistently follow recommended screening guidelines, with many uncertain about the benefits of testing. Key barriers included confusion about testing recommendations and concerns about delaying HIV treatment, suggesting that doctors need better education about the importance of early detection.

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Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review

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This study examines rare fungal infections in patients with Chronic Granulomatous Disease, a genetic disorder affecting the immune system. Researchers found that these patients develop various unusual fungal infections despite taking preventive antifungal medications. The infections are difficult to diagnose, often requiring surgical procedures, but can sometimes be cured through stem cell transplantation combined with intensive antifungal treatment.

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Prevalence of Tinea pedis in military personnel: a systematic review and meta-analysis

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Athlete’s foot is a common fungal infection affecting military personnel at rates around 17% globally. Military environments create perfect conditions for this infection through close living quarters, humidity from sweat and boots, and shared facilities. The study found that regions with hot, humid climates have higher infection rates, and proper diagnosis using both microscopy and culture tests is important for accurate detection. Improved hygiene, better-designed footwear, and access to antifungal treatments can significantly reduce infection rates in military settings.

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Keep the Hospital Clean: Diagnostic Performance of Ten Different Molecular and Culture-Based Methods to Detect Candidozyma (Candida) auris

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This study tested different methods to detect a dangerous hospital fungus called Candida auris. Researchers compared growing the fungus on special plates and using molecular tests on patient samples. They found that molecular tests (qPCR) were most sensitive for detecting low levels of the fungus, while growing it on special plates worked well for higher levels. The best approach depends on whether a hospital is dealing with an outbreak or routine screening.

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