Research Keyword: dermatology

Potential Cosmetic Applications of the Combined Extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and Several Asian Plants

Researchers created a combination extract from four Asian plants including ginseng, medicinal mushrooms, and other herbs to treat acne. They tested this blend in laboratories and found it effectively killed acne-causing bacteria, reduced skin inflammation, repaired the skin barrier, and reduced oily skin production. The extract was safe for skin cells and appeared to work as well as or better than standard treatments.

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Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne

This study tested two supplements for treating non-cystic acne: one containing probiotics and herbs, and another based on myoinositol and medicinal plants. Both supplements significantly reduced acne lesions and improved gut health by increasing beneficial bacteria and beneficial fatty acids produced by these bacteria. The myoinositol-based supplement also reduced hormone precursors related to acne development. These findings suggest that supporting gut health may be an effective way to treat acne.

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Assessment of Cosmetic Properties and Safety of Use of Model Washing Gels with Reishi, Maitake and Lion’s Mane Extracts

Researchers tested three medicinal mushrooms (Maitake, Lion’s Mane, and Reishi) as ingredients in washing gels to improve their safety and effectiveness. The study found that these mushroom extracts reduced skin irritation, improved skin moisturization, and boosted antioxidant protection better than gels without them. Maitake extract performed particularly well, showing the strongest antioxidant properties. These findings suggest mushroom extracts could be valuable natural alternatives in everyday skincare products.

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The Benefits of a Multimechanistic Antiaging Skin Technology

Researchers tested a special antiaging face serum containing multiple skin-boosting ingredients on 50 women over 24 weeks. The serum significantly improved skin hydration, firmness, texture, and reduced wrinkles and fine lines. Results showed improvements as early as one week, with continued benefits throughout the study, and the product was very well tolerated with no irritation or side effects.

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Electrospun Membranes Loaded with Melanin Derived from Pecan Nutshell (Carya illinoinensis) Residues for Skin-Care Applications

Researchers developed new skincare membranes by combining pecan shell waste with advanced fiber technology. These membranes harness melanin from the shells to create materials with strong antioxidant and antibacterial properties that could protect skin from aging and infections. The innovation demonstrates how agricultural waste can be transformed into valuable cosmetic products that are both effective and environmentally friendly.

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Optimized protein extraction protocol from human skin samples

Researchers developed an improved method for extracting and analyzing proteins from human skin samples. Using specialized equipment and chemical treatments, they were able to identify about 6,000 different proteins in skin tissue, which is significantly more than previous methods could detect. This new protocol is particularly useful for studying skin diseases like fungal infections and could help identify new treatments by revealing how proteins change in diseased skin.

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Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur

Malassezia furfur is a common skin fungus that can change from round yeast cells to thread-like filaments. When it becomes thread-like, it produces a special enzyme called MfSAP2 that damages the proteins holding together the dead skin cells that form our skin’s protective barrier. This damage may be responsible for the patches and discoloration seen in pityriasis versicolor, a common skin condition.

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Onychomycosis with gray-green staining caused by Fusarium solani

A 76-year-old gardener developed a gray-green discolored thumbnail that was initially thought to be a bacterial infection. Testing revealed it was actually caused by a fungus called Fusarium solani, which unusually produced dark-green colonies. The patient was successfully treated by removing the affected nail and applying an antifungal medication, demonstrating the importance of proper fungal testing for nail infections.

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Deep cutaneous fungal infection in an immunocompetent individual caused by a biological pesticide: a rare case report

A 66-year-old farmer developed a deep skin fungal infection from a biological pesticide she used for over 10 years. The pesticide contained a fungus called Purpureocillium lilacinum, which is normally harmless to healthy people but caused repeated skin lesions on her face and arms. She was successfully treated with antifungal medication (itraconazole) for three months, and her skin fully healed without returning. This is the first reported case showing that biological pesticides can pose health risks to workers who handle them regularly.

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Photo Quiz: Asteroid bodies in a skin biopsy of a farmer

A farmer developed nodular skin lesions two weeks after a wrist injury during farming activities, which turned out to be sporotrichosis, a fungal infection caused by Sporothrix globosa. Skin biopsy revealed characteristic structures called asteroid bodies that helped suggest the diagnosis. The infection was confirmed through fungal culture and DNA testing, and was successfully treated with potassium iodide over six months.

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