Research Keyword: dematiaceous fungi

Phaeohyphomycosis caused by Rhinocladiella similis mimicking Sporotrichosis

A 34-year-old factory worker developed multiple nodules on his hand following an injury, initially suspected to be sporotrichosis, a common fungal infection. Through laboratory testing including fungal culture and genetic sequencing, doctors identified the actual cause as a rare fungus called Rhinocladiella similis. The patient was successfully treated with antifungal medication and showed gradual improvement. This is the first case of this fungal infection reported in India.

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Two Cases of Curvularia geniculata Keratitis Successfully Treated with Natamycin-Based Therapy

This report describes two patients who developed rare fungal eye infections caused by Curvularia geniculata after eye injuries. Both patients were successfully treated with antifungal eye drops, particularly natamycin. Molecular testing confirmed the specific fungus causing the infection. Both patients recovered well with excellent vision restoration, demonstrating that proper diagnosis and targeted antifungal treatment can effectively manage this rare condition.

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Establishment of epidemiological cutoff values for Fonsecaea pedrosoi, the primary etiologic agent of chromoblastomycosis, and eight antifungal medications

Chromoblastomycosis is a serious fungal skin infection caused by a fungus called Fonsecaea pedrosoi, particularly affecting people in tropical regions and those in poverty. Researchers from multiple countries tested 148 samples of this fungus against eight different antifungal medications to determine how well each drug works. They established baseline measurements that doctors can use to determine if a patient’s fungal infection might not respond well to standard treatments, helping guide better treatment decisions.

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Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient

An 82-year-old dialysis patient developed an infection caused by a rare black mold called Arthrocladium tropicale, which had never been documented in humans before. The infection came from poor environmental conditions including moisture and ant infestations near the patient’s dialysis supply storage area. Doctors identified the fungus using genetic testing and treated it successfully with antifungal medication combined with removal of the dialysis catheter. This case shows how important it is to keep dialysis equipment areas clean and dry to prevent rare infections.

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Successful Treatment of Fungal Dermatitis in a Bottlenose Dolphin (Tursiops truncatus)

A bottlenose dolphin at a Japanese aquarium developed a serious fungal infection on its tail fin while suffering from severe digestive problems and weight loss. The infection was caused by two types of fungi that are normally hard to treat because they resist many antifungal medications. Veterinarians successfully treated the dolphin using a combination of two antifungal drugs (voriconazole and terbinafine), surgical removal of dead tissue, and daily wound cleaning with special solutions. The dolphin’s wound eventually healed completely, and this is the first documented successful treatment of these particular fungal infections in bottlenose dolphins.

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Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient

A peritoneal dialysis patient contracted a rare fungal infection caused by Arthrocladium tropicale, a mold found in damp environments and associated with ant nests. The infection was diagnosed through microscopy and genetic testing, revealing resistance to one antifungal drug but susceptibility to amphotericin B. Treatment with this antibiotic and removal of the dialysis catheter led to full recovery, highlighting the importance of keeping medical equipment storage areas dry and pest-free.

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Two Cases of Curvularia geniculata Keratitis Successfully Treated with Natamycin-Based Therapy

Two patients developed rare fungal eye infections caused by Curvularia geniculata after eye injuries from plant material. The infections caused corneal ulcers with characteristic feathery infiltrates. Both patients were successfully treated using natamycin eyedrops, either alone or combined with voriconazole, and both recovered excellent vision. Accurate identification of the fungus using genetic testing confirmed the diagnosis and helped guide treatment decisions.

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Systematic Review of Tinea Nigra: A Clinical Approach

Tinea nigra is a rare fungal skin infection that causes dark spots, usually on the palms, and is most common in tropical regions. It primarily affects younger people and women. The infection is easily diagnosed using microscopic examination and treated successfully with topical antifungal creams like ketoconazole or Whitfield’s ointment, typically clearing within 4 weeks.

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Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient

An 82-year-old dialysis patient developed an unusual infection caused by a black mold called Arthrocladium tropicale, which had never been documented in humans before. The infection was traced to poor storage conditions and ant infestations near the patient’s dialysis supplies in Thailand during rainy season. Doctors identified the rare fungus using molecular genetic testing and treated it successfully with antifungal medication combined with removal of the dialysis catheter. This case highlights the importance of keeping dialysis equipment in clean, dry environments and preventing pest access to prevent serious infections.

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A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole

A 71-year-old woodworker developed a serious eye infection caused by a rare fungus called Alternaria citri that damaged his cornea. Doctors identified the fungus using genetic testing and treated it with the antifungal drug voriconazole combined with surgery. After one year, his vision improved and the infection did not return, marking the first documented case of this particular fungal infection in humans.

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