Research Keyword: de novo sequencing

Exploring the Siderophore Portfolio for Mass Spectrometry-Based Diagnosis of Scedosporiosis and Lomentosporiosis

Two dangerous opportunistic fungi that cause serious infections in vulnerable patients produce distinct chemical compounds called siderophores to help them acquire iron from their hosts. Researchers used advanced mass spectrometry techniques to detect and measure these compounds, finding that one fungus produces significantly more of these iron-scavenging molecules, which may explain why it causes more severe infections. These siderophores could potentially be used as diagnostic markers in medical laboratories to quickly identify these infections in patient samples.

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De novo Genome Assembly and Annotation of 12 Fungi Associated with Fruit Tree Decline Syndrome in ON, Canada

Apple and stone fruit trees in Ontario have been dying at alarming rates since 2016. Researchers sequenced and analyzed the genetic code of 12 different fungi suspected of causing this decline. This study provides the first complete genetic blueprints for several fungal species, helping farmers and scientists better understand what causes the disease and develop ways to prevent it.

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