cytotoxicity – mycolab.ai

Green Synthesis of Copper Nanoparticles from the Aqueous Extract of Lonicera japonica Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity

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Scientists created tiny copper particles using honeysuckle plant extract in an environmentally friendly way. These particles work well for cleaning dyes from water and killing harmful bacteria and fungi. However, they can be toxic to human cells at high concentrations, so careful dosing is important for medical applications.

The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

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This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

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This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

Effect of Selected Entomopathogenic Fungal Species on Embryonic Development of Ascaris suum (Nematoda)

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Researchers tested five types of fungi that naturally attack insects to see if they could control Ascaris roundworm eggs that contaminate pig farms and pose health risks. While none of the fungi directly killed the eggs, two species (Isaria fumosorosea and Metarhizium robertsii) successfully slowed egg development and showed potential for controlling parasites. These fungi appear to work by producing toxic compounds and enzymes rather than by penetrating the egg shells directly.

Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity

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Researchers tested a medicinal mushroom extract (Reishi/Ganoderma lucidum) to see if it could fight cancer and bacterial infections. The extract showed promising results, being particularly effective against blood cancer and breast cancer cells while being less toxic to normal healthy cells. It also killed bacteria better than some standard antibiotics, suggesting it could potentially be developed into a new type of medicine for treating cancer and infections.

Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

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Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Ganoderma lucidum Extracts from High-Altitude Regions of Nepal

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Researchers studied a medicinal mushroom called Ganoderma lucidum (Reishi) collected from high mountains in Nepal to understand its health benefits. They tested different ways to extract beneficial compounds from the mushroom and found that using ethanol was most effective. The extracts showed strong cancer-fighting properties against cervical cancer cells and powerful antioxidant effects that may help protect the body from damage. These findings suggest this Himalayan mushroom has real therapeutic potential for treating cancer and other diseases.

Evaluation of resistance patterns and bioremoval efficiency of hydrocarbons and heavy metals by the mycobiome of petroleum refining wastewater in Jazan with assessment of molecular typing and cytotoxicity of Scedosporium apiospermum JAZ-20

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Scientists isolated fungi from oil refinery wastewater in Saudi Arabia and discovered that a fungus called Scedosporium apiospermum JAZ-20 is exceptionally good at removing harmful metals and oil pollutants from contaminated water. This fungus was also tested on human cancer cells and showed promise as a potential anti-cancer agent while being relatively safe. The research suggests this fungus could be used as an eco-friendly solution to clean up polluted industrial wastewater.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

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Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Anticancer Activity of Solvent Extracts of Hexogonia glabra against Cervical Cancer Cell Lines

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Researchers tested extracts from a wild mushroom species called Hexogonia glabra against cervical cancer cells in the laboratory. The ethanolic extract was most effective, killing cancer cells by triggering apoptosis (programmed cell death) and activating genes that fight cancer. The mushroom extracts showed strong anticancer effects without harming normal cells, suggesting it could be a promising source for developing new cancer drugs.

Research Keyword: cytotoxicity